The Mount Sinai Regional Comprehensive Hemophilia Treatment Center (HTC) is recognized by the World Federation of Hemophilia as an International Hemophilia Training Center, one of a handful in the United States, and, as such, has hosted professionals from Thailand, Russia, India, and Brazil for mini-sabbatical programs.

The Mount Sinai HTC is part of a network of federally funded treatment centers in the United States and the Caribbean. Mount Sinai is the Regional Grantee for Region II, which consists of 14 treatment centers located in New York, New Jersey, and Puerto Rico.

All treatment centers provide comprehensive care to patients with bleeding disorders, the most common of which is hemophilia. Comprehensive care consists of a multidisciplinary approach to care concentrated in one visit. Patients with severe forms of hemophilia are seen one or two times per year, moderate forms one time per year or one time per two years, and mild cases are seen every other year. Studies have shown that the development and implementation of the comprehensive care model for patients with bleeding disorders have standardized treatment modalities and provided these patients with the ability to lead close to normal lives and be productive members of society. In addition, as a result of the Hemophilia Treatment Center (HTC) structure, the relationship between research and clinical practice is fluid, with rapid introduction into the clinical setting of new modalities for diagnosis and treatment.

At the Mount Sinai HTC, patients are seen by the Adult or the Pediatric Hematologist, an Orthopedist, the Infectious Disease Consultant, if needed, a Psychiatrist by appointment, Registered Nurses, a Physical Therapist, Social Workers, a Dental Hygienist, Vocational Counselor, Geneticist, and the Clinical Coordinator.

Additionally, a large number of clinical studies are under way in the Treatment Center which include studies into the epidemiology of inherited bleeding disorders, evaluation of new therapeutic interventions for these disorders, and studies aimed at understanding, treating, and preventing the complications of bleeding disorders.