Iontophoresis
Hyperhidrosis - iontophoresis; Excessive sweating - iontophoresis
Iontophoresis is the process of passing a weak electrical current through the skin. Iontophoresis has a variety of uses in medicine. This article discusses the use of iontophoresis to decrease sweating by blocking sweat glands.
Description
The area to be treated is placed into water. A gentle current of electricity passes through the water. A technician carefully and gradually increases the electrical current until you feel a light tingling sensation.
The therapy lasts about 30 minutes and requires several sessions each week.
How iontophoresis works is not exactly known. It is thought that the process somehow plugs the sweat glands and temporarily prevents you from sweating in the area that has been treated.
Iontophoresis units are also available for home use. If you use a unit at home, be sure to follow the instructions that come with the machine.
Why the Procedure Is Performed
Iontophoresis may be used to treat excessive sweating (hyperhidrosis) of the hands, underarms, and feet.
Risks
Side effects are rare but may include skin irritation, dryness, and blistering. Tingling may continue even after the treatment has ended.
References
James WD. Diseases of the skin appendages. In: James WD, ed. Andrews' Diseases of the Skin: Clinical Dermatology. 14th ed. Philadelphia, PA: Elsevier; 2026:chap 28.
Miller JL. Diseases of the eccrine and apocrine sweat glands. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 5th ed. Philadelphia, PA: Elsevier; 2025:chap 39.
Pollack SV. Electrosurgery. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 5th ed. Philadelphia, PA: Elsevier; 2025:chap 140.
Version Info
Last reviewed on: 6/3/2025
Reviewed by: Ramin Fathi, MD, FAAD, Director, Phoenix Surgical Dermatology Group, Phoenix, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
