Neurofibromatosis-1

NF1; Von Recklinghausen neurofibromatosis

Neurofibromatosis-1 (NF1) is an inherited disorder in which nerve tissue tumors (neurofibromas) form in the:

  • Bottom layer of skin (subcutaneous tissue)
  • Nerves from the brain (cranial nerves) and spinal cord (spinal root nerves)
Neurofibroma

Neurofibroma is a tumor or growth located along a nerve or nervous tissue. It is an inherited disorder. If left unchecked, a neurofibroma can cause severe nerve damage leading to loss of function to the area stimulated by that nerve.

Neurofibromatosis - giant cafe-au-lait spot

People with neurofibromatosis often have more than 6 light brown spots -- cafe-au-lait spots -- larger than 1.5 centimeters. This is a picture of a giant cafe-au-lait spot on a person with neurofibromatosis.

Causes

Symptoms

Exams and Tests

Treatment

Support Groups

Outlook (Prognosis)

Possible Complications

When to Contact a Medical Professional

Prevention