Meprobamate is a drug used to treat anxiety. Meprobamate overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.
This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Meprobamate can be poisonous in large amounts.
Below are symptoms of a meprobamate overdose in different parts of the body.
EYES, EARS, NOSE, AND THROAT
- Blurred vision
- Double vision
- Rapid side-to-side movement of the eyes
STOMACH AND INTESTINES
HEART AND BLOOD
- Low blood pressure
- Pounding heartbeat (palpitations)
- Rapid heart rate
- Slow heart rate
- Labored breathing
- Slowed breathing
- Coma (decreased level of consciousness and lack of responsiveness)
- Lack of alertness (stupor)
- Slurred speech
- Uncoordinated movement
Seek medical help right away. Do not make the person throw up unless poison control or a health care provider tells you to.
Before Calling Emergency
Have this information ready:
- Person's age, weight, and condition
- Name of the medicine (strength, if known)
- Time it was swallowed
- Amount swallowed
Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
Take the container with you to the hospital, if possible.
The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.
Tests that may be done include:
- Blood and urine tests
- Chest x-ray
- CT scan
- ECG (electrocardiogram, or heart tracing)
Treatment may include:
- Fluids through a vein (by IV)
- Medicine to treat symptoms
- Activated charcoal
- Breathing support, including tube through the mouth into the lungs and connected to a breathing machine (ventilator)
- Kidney dialysis in severe cases
How well someone does depends on the amount of meprobamate swallowed and how quickly treatment is received. The sooner medical help is given, the better the chance for recovery.
With proper care, most people recover. But, recovery may be more difficult in people with aplastic anemia. This is because their bone marrow does not produce enough red blood cells.
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Gussow L, Carlson A. Sedative hypnotics. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 159.
Last reviewed on: 11/13/2021
Reviewed by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.