Lymphadenopathy; Lymphofollicular hypertrophy
Lymphofollicular hyperplasia is an increase in the number of cells found in lymph node. These follicles contain normal white blood cells called lymphocytes. Your body produces more lymphocytes to help prevent bacteria, viruses, and other types of germs from entering the bloodstream.
Winter JN. Approach to the patient with lymphadenopathy and splenomegaly. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 159.
Last reviewed on: 9/1/2021
Reviewed by: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.