Glomus tympanum tumor
Paraganglioma - glomus tympanum
A glomus tympanum tumor is a tumor of the middle ear and bone behind the ear (mastoid).
A glomus tympanum tumor grows in the temporal bone of the skull, behind the eardrum (tympanic membrane).
This area contains nerve fibers (glomus bodies) that normally respond to changes in body temperature or blood pressure.
These tumors most often occur late in life, around age 60 or 70, but they can appear at any age.
The cause of a glomus tympanum tumor is unknown. In most cases, there are no known risk factors. Glomus tumors have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).
Symptoms may include:
- Hearing problems or loss
- Ringing in the ear (pulsatile tinnitus)
- Weakness or loss of movement in the face (facial nerve palsy)
Exams and Tests
Glomus tympanum tumors are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms.
People who have surgery tend to do well. More than 90% of people with glomus tympanum tumors are cured.
The most common complication is hearing loss.
Nerve damage, which may be caused by the tumor itself or damage during surgery, rarely occurs. Nerve damage can lead to
When to Contact a Medical Professional
Call your health care provider if you notice:
- Difficulty with hearing or swallowing
- Problems with the muscles in your face
- Pulsing sensation in your ear
Marsh M, Jenkins HA. Temporal bone neoplasms and lateral cranial base surgery. In: Flint PW, Haughey BH, Lund V, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 176.
Rucker JC, Thurtell MJ. Cranial neuropathies. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 104.
Zanotti B, Verlicchi A, Gerosa M. Glomus tumors. In: Winn HR, ed. Youmans and Winn Neurological Surgery. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 156.
Last reviewed on: 10/30/2019
Reviewed by: Josef Shargorodsky, MD, MPH, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.