• Press Release

Mount Sinai Health System Collaborates with OpenEvidence to Provide Evidence-Based Knowledge Within Electronic Medical Record

Collaboration extends access to all clinical users, including nurses and pharmacists

  • New York, NY, and Miami, FL
  • (March 31, 2026)

Mount Sinai Health System (Mount Sinai), one of the largest academic medical systems in New York and the nation, and OpenEvidence, the leading AI-powered medical search and clinical decision-support platform, today announced a collaboration to make OpenEvidence accessible directly from within the electronic health record across Mount Sinai, providing clinicians with on-demand evidence and clinical insights. The collaboration marks the first enterprise-scale OpenEvidence deployment to extend access across the full clinical care team—including physicians, registered nurses, and pharmacists—bringing trusted, evidence-based answers to more of the professionals involved in patient care. 

OpenEvidence will enable Mount Sinai clinical staff to ask medical questions in natural language and receive answers grounded in peer-reviewed literature and clinical guidelines within their existing Epic workflow. Physicians, nurses, and pharmacists face clinical questions throughout every shift that require fast access to information. This collaboration recognizes every member of the care team supporting the patient deserves such access.  

Mount Sinai Health System encompasses seven hospitals, the Icahn School of Medicine at Mount Sinai which includes a Graduate School of Biomedical Sciences, and the Mount Sinai Phillips School of Nursing. They are among the first academic medical systems in the U.S. to establish a dedicated department of AI—the Windreich Department of AI and Human Health—and recently opened the Hamilton and Amabel James Center for Artificial Intelligence and Human Health on its Manhattan campus as a commitment to advancing innovation that strengthens quality, safety, and patient-centered care across the full care continuum. 

"At Mount Sinai, we prioritize innovation that solves core clinical problems and scales across the entire delivery system. Implementing OpenEvidence provides our pharmacists, nurses, and physicians with a unified, trusted platform for evidence-based decision-making, reinforcing our mission to lead the way in safe and effective clinical AI,” said Nicholas Gavin, Vice President, Chief Clinical Innovation Officer of Mount Sinai Health System. “Our partnership with OpenEvidence is a vital step in democratizing access to the latest clinical evidence for every member of the Mount Sinai care team. We are committed to equipping our clinicians with intuitive, AI-powered tools that reduce the cognitive burden of information retrieval and allow them to focus on what matters most—the patient.” 

“We are committed to advancing AI that is not only innovative but clinically meaningful, trusted, and seamlessly integrated into care delivery. By embedding OpenEvidence directly into the clinical workflow, we are equipping every member of the care team with real-time access to rigorously sourced, evidence-based insights,” said Girish N. Nadkarni, MD, MPH, the Chief AI Officer of the Mount Sinai Health System and Chair of the Windreich Department of Artificial Intelligence and Human Health at the Icahn School of Medicine at Mount Sinai and Director of the Hasso Plattner Institute for Digital Health at Mount Sinai. “This collaboration reflects our broader vision to responsibly scale AI across the health system in a way that enhances clinical decision-making, reduces cognitive burden, and ultimately improves outcomes for our patients.” 

“Mount Sinai is an elite institution that demands elite technology. The collaboration with OpenEvidence sets a new standard of evidence-based care by providing access to our world class AI to all clinicians of one of the greatest academic medical systems in the world” said Daniel Nadler, CEO and Founder of OpenEvidence. “This agreement is our first to expand access to the entire care team, including all Mount Sinai nurses and pharmacists. This is the new baseline for what a modern hospital looks like.” 

 

About OpenEvidence 

OpenEvidence is the most widely used medical AI platform among U.S. physicians, and is trusted by hundreds of thousands of verified clinicians to make high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature. OpenEvidence was founded with the mission to organize and expand the world's collective medical knowledge. Learn more at openevidence.com.


About the Mount Sinai Health System

Mount Sinai Health System is one of the nation’s leading integrated academic health systems and one of the largest in the New York metropolitan area. The Health System includes approximately 48,000 employees, more than 9,000 physicians, and 8,600 nurses across seven hospitals, more than 400 outpatient practices, over 600 research and clinical laboratories, a school of nursing, and schools of medicine and graduate school of biomedical sciences.  

As a leading learning health system, Mount Sinai combines clinical expertise with scientific discovery to improve patient care while training the next generation of health care and biomedical leaders. The Health System provides care across every stage of life, from prenatal care through geriatrics, while advancing personalized medicine through artificial intelligence, data science, and biomedical research.  

Mount Sinai is consistently recognized among the nation’s leading academic health systems for patient care, research, and education. The Mount Sinai Hospital is ranked No. 1 in New York and recognized as one of the world’s top Smart Hospital by Newsweek. The Icahn School of Medicine at Mount Sinai ranks No. 11 among U.S. medical schools for National Institutes of Health (NIH) funding and No. 1 among freestanding medical schools, reflecting the strength of its scientific enterprise and leadership in biomedical research. 

For more information, visit https://www.mountsinai.org or find Mount Sinai on Facebook, Instagram, LinkedIn, X, and YouTube. To listen to news and stories from Mount Sinai, visit the Mount Sinai Podcast Network.