Mount Sinai and RenalytixAI Launch Groundbreaking Artificial Intelligence Solution For Improved Kidney Disease Management and Patient Care
• Artificial Intelligence (AI) will be deployed against Mount Sinai’s massive patient data warehouse biorepository and to innovate more accurate disease detection and management for introduction in 2019 • Kidney disease is a public health crisis affecting an estimated 12% or 120 million of the US and European populations with 90% of patients unaware they are at-risk • Approximately half of new dialysis patients in the United States have never seen a specialist despite over $100 billion in costs being attributed to chronic kidney disease management annually
Mount Sinai Health System (MSHS) and RenalytixAI, Plc today have entered into an exclusive multi-year license and collaboration to commercialize artificial intelligence solutions to improve kidney disease detection, management and treatment for patients with diabetes and other at-risk, large-scale patient populations.
The partnership will leverage MSHS’s massive data warehouse containing over 3,000,000 patient health records and 43,000 patient records in the BioMeTM BioBank repository, and using de-identified clinical data, will create an advanced learning system to monitor and flag patients at risk for kidney disease and costly unplanned “crashes” into dialysis. The first product launch is anticipated in Q2 2019 targeting the heart of the $98 billion in preventable dialysis and chronic kidney disease costs. Additional major U.S. based healthcare systems are expected to participate in clinical utility data development and product launch.
“Our ability to apply the power of artificial intelligence against such a deep repository of clinical data in combination with prognostic biomarkers has the potential to change the game for all of our patients with diabetes and other populations at risk for kidney disease,” said Barbara Murphy, MD, Dean for Clinical Integration and Population Health and Chair for the Department of Medicine at the Icahn School of Medicine at Mount Sinai (ISMMS), and Chair of the RenalytixAI Scientific Advisory Board.
“This partnership represents a powerful model for translating, validating and driving high-impact medical technology as quickly and safely as possible to benefit patients, care providers and payers,” said James McCullough, co-Founder and Chief Executive Officer of RenalytixAI.
This is a significant partnership for RenalytixAI with one of the largest hospital groups in the United States. The technology alongside the Mount Sinai patient database will improve patient care in End Stage Renal Disease, a significant unmet medical need. The fact that so many patients on dialysis have never seen a specialist has to change both from a patient care and cost perspective. I believe that this partnership will result in RenalytixAI being leaders in the field of kidney care, alongside Mount Sinai,” said Julian Baines, RenalytixAI Executive Chairman.
Approximately 1 million patients cared for in the MSHS are either diagnosed with Type II diabetes or are of African ancestry, two of the major at-risk population segments for kidney disease. The MSHS is one of the largest integrated healthcare systems in the U.S. with over 6,500 physicians and 6,300 faculty.
“We’re proud to be advancing prognostics at the nexus of artificial intelligence and healthcare analytics. The accomplished innovators and rich data resources of Mount Sinai combined with the expertise and vision of our colleagues at RenalytixAI are evolving the development of cutting-edge renal prognostics for the benefit of patients and healthcare globally,” said Erik Lium, PhD, Senior Vice President at Mount Sinai Innovation Partners.
RenalytixAI expects to pursue expanded clinical utility trials through collaborations with leading academic medical centers, pharmaceutical and patient advocacy organizations in the United States and Europe beginning in 2018, followed by submission of product applications for review by the U.S. Food and Drug Administration.
RenalytixAI Plc was established in 2018 to commercialize advanced artificial intelligence decision support and clinical management tools for improvements in patient care and cost savings in kidney disease globally.
About Mount Sinai Innovation Partners (MSIP)
MSIP is responsible for driving the real-world application and commercialization of Mount Sinai discoveries and inventions, and the development of research partnerships with industry. Our aim is to translate discoveries and inventions into health care products and services that benefit patients and society. MSIP is accountable for the full spectrum of commercialization activities required to bring Mount Sinai inventions to life. These activities include evaluating, patenting, marketing and licensing new technologies building research, collaborations and partnerships with commercial and nonprofit entities, material transfer and confidentiality, coaching innovators to advance commercially-relevant translational discoveries, and actively fostering an ecosystem of entrepreneurship within the Mount Sinai research and health system communities. For more information, visit www.ip.mountsinai.org.
About the Mount Sinai Health System
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, over 400 outpatient practices, nearly 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it.
Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes approximately 7,300 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties.
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