"How DNA Tests Can Help Physicians Detect Infectious Diseases Faster"-Megan Knowles
Hospitals are starting to look to genetic sequencing services to identify pathogens that make patients sick. Karius, a life sciences company focusing on infectious disease diagnostics with genomics, uses DNA tests that can deliver results quicker than traditional lab methods. “This is pretty bleeding-edge stuff,” said Joel Dudley, PhD director of the Mount Sinai Institute for Next Generation Healthcare and executive vice president of precision health for the Mount Sinai Health System. But if scientists look to sequencing and software to identify microbes from DNA alone, they first need to develop massive genetic databases that evolve with the pathogens. "We're just beginning to get data sets big enough to have clinical utility," Dr. Dudley said. "So there's still work to be done. But it's a very promising approach for getting diagnoses more quickly."
- Joel Dudley, PhD, Director, Institute for Next Generation Healthcare, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System
About the Mount Sinai Health System
The Mount Sinai Health System is New York City's largest integrated delivery system, encompassing eight hospitals, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region. Mount Sinai's vision is to produce the safest care, the highest quality, the highest satisfaction, the best access and the best value of any health system in the nation. The Health System includes approximately 7,480 primary and specialty care physicians; 11 joint-venture ambulatory surgery centers; more than 410 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers. The Icahn School of Medicine is one of three medical schools that have earned distinction by multiple indicators: ranked in the top 20 by U.S. News & World Report's "Best Medical Schools", aligned with a U.S. News & World Report's "Honor Roll" Hospital, No. 12 in the nation for National Institutes of Health funding, and among the top 10 most innovative research institutions as ranked by the journal Nature in its Nature Innovation Index. This reflects a special level of excellence in education, clinical practice, and research. The Mount Sinai Hospital is ranked No. 14 on U.S. News & World Report's "Honor Roll" of top U.S. hospitals; it is one of the nation's top 20 hospitals in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Geriatrics, Gynecology, Nephrology, Neurology/Neurosurgery, and Orthopedics in the 2019-2020 "Best Hospitals" issue. Mount Sinai's Kravis Children's Hospital also is ranked nationally in five out of ten pediatric specialties by U.S. News & World Report. The New York Eye and Ear Infirmary of Mount Sinai is ranked 12th nationally for Ophthalmology and the South Nassau Communities Hospital is ranked 35th nationally for Urology. Mount Sinai Beth Israel, Mount Sinai St. Luke's, Mount Sinai West, and South Nassau Communities Hospital are ranked regionally.