"How DNA Tests Can Help Physicians Detect Infectious Diseases Faster"-Megan Knowles
Hospitals are starting to look to genetic sequencing services to identify pathogens that make patients sick. Karius, a life sciences company focusing on infectious disease diagnostics with genomics, uses DNA tests that can deliver results quicker than traditional lab methods. “This is pretty bleeding-edge stuff,” said Joel Dudley, PhD director of the Mount Sinai Institute for Next Generation Healthcare and executive vice president of precision health for the Mount Sinai Health System. But if scientists look to sequencing and software to identify microbes from DNA alone, they first need to develop massive genetic databases that evolve with the pathogens. "We're just beginning to get data sets big enough to have clinical utility," Dr. Dudley said. "So there's still work to be done. But it's a very promising approach for getting diagnoses more quickly."
- Joel Dudley, PhD, Director, Institute for Next Generation Healthcare, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System
About the Mount Sinai Health System
The Mount Sinai Health System is New York City's largest academic medical system, encompassing eight hospitals, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region. Mount Sinai advances medicine and health through unrivaled education and translational research and discovery to deliver care that is the safest, highest-quality, most accessible and equitable, and the best value of any health system in the nation. The Health System includes approximately 7,300 primary and specialty care physicians; 13 joint-venture ambulatory surgery centers; more than 415 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. The Mount Sinai Hospital is ranked on U.S. News & World Report's "Honor Roll" of the top 20 U.S. hospitals and is top in the nation by specialty: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. Mount Sinai Kravis Children's Hospital is ranked in U.S. News & World Report’s “Best Children’s Hospitals” among the country’s best in four out of 10 pediatric specialties. The Icahn School of Medicine is one of three medical schools that have earned distinction by multiple indicators: ranked in the top 20 by U.S. News & World Report's "Best Medical Schools," aligned with a U.S. News & World Report "Honor Roll" Hospital, and No. 14 in the nation for National Institutes of Health funding. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.