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Dr. Scott L. Friedman: “Obesity-Cancer Link Detailed”

  • The Scientist
  • (June 26, 2013)

According to new research published today in Nature, obesity can cause the circulation of DNA-damaging metabolites through the gut and liver and initiate inflammatory and tumor-promoting factors that make mice more susceptible to liver cancer. “The findings implicate hepatic stellate cells as an important transducer of the signals that emerge from the microbiome in altering the microenvironment to favor the emergence of cancer,” said Physician and Liver Disease Researcher Scott Friedman, MD, of the Icahn School of Medicine at Mount Sinai, who did not participate in the research. Learn more