Lung-cancer Survival Worse in Patients with Pulmonary Fibrosis
According to researchers at the Icahn School of Medicine at Mount Sinai, non-small cell lung cancer presents differently in patients with idiopathic pulmonary fibrosis, who also have higher overall and lung-cancer mortality. "We found that patients with IPF and lung cancer have a greater proportion of early stage disease of squamous histology in a lower lobe distribution," said Stacey-Ann Brown, MD, assistant professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai. The study, published in the Annals of the American Thoracic Society, showed lung cancer prevalence may be as high as 30 percent in patients with IPF. Dr. Brown added, "This atypical distribution may need to be incorporated into risk models for lung nodule management in IPF patients.
— Stacey-Ann Brown, MD, MPH, Assistant Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai.
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