Icahn School of Medicine at Mount Sinai Receives $1 Million as an Inaugural Recipient of NYFIRST Medical School Grant From New York State
Julius C. Hedden, III, PhD, recruited to Mount Sinai to apply innovative imaging techniques to research Alzheimer’s disease and other dementias
Governor Andrew Cuomo has announced the Icahn School of Medicine at Mount Sinai (ISMMS) as one of the inaugural grant recipients from the New York Fund for Innovation in Research and Scientific Talent (NYFIRST). NYFIRST is a $15 million medical school capital funding program to encourage recruitment and retention of exceptional life sciences researchers who are focused on translational research by supporting the establishment or upgrading of their laboratories. Each of the inaugural recipient institutions—Mount Sinai, Columbia University, and the University of Rochester—is bringing top-notch translational research talent to New York from prominent research institutions across the country.
Through the NYFIRST award, the Icahn School of Medicine has recruited Julius C. Hedden III, PhD, from Harvard Medical School in Boston. Dr. Hedden’s research focuses on applying innovative imaging techniques for age-related neurodegenerative disorders like Alzheimer’s disease. His laboratory at Mount Sinai focuses on integrating multiple brain markers to help build a comprehensive picture of the relationship between brain function and cognition during aging and neurodegenerative disease. Dr. Hedden’s lab is part of the school’s Translational and Molecular Imaging Institute, an institute that provides and assists the research community’s access to and use of a comprehensive, state-of-the-art, dynamic imaging infrastructure with a focus on using multimodality imaging for brain, cancer, and cardiovascular research.
“This generous investment by New York State made it possible for Icahn School of Medicine to recruit Dr. Hedden, a world leader in the use of advanced brain imaging to diagnose Alzheimer’s disease and other dementias,” says Eric J. Nestler, MD, PhD, Nash Family Professor of Neuroscience, Director of The Friedman Brain Institute, and Dean for Academic and Scientific Affairs at the Icahn School of Medicine at Mount Sinai. “He will play an essential role in guiding our multidisciplinary research team in the search for new treatments for these devastating illnesses. We are thrilled to have him join our ranks and we look forward to partnering with the state in an effort to help New York become the epicenter for the biosciences.”
Dr. Hedden’s published work, which has appeared in more than 70 primary research articles, examines behavioral and neuroimaging measures of age-related changes in memory and executive control processes. His current research integrates measures of functional magnetic resonance imaging (MRI) with positron emission tomography (PET) markers of tau and amyloid accumulation (the hallmark proteins associated with Alzheimer’s), PET markers of dopamine dysfunction, PET markers of glucose metabolism, and MRI markers of white matter to target potential preclinical Alzheimer’s-related neuropathology in otherwise normal older individuals.
NYFIRST makes a maximum grant of $1 million available to eligible institutional applicants (medical schools in New York State) to modernize, renovate, and upgrade laboratory facilities to attract world-class scientists. Program grant awards are made through a competitive grant solicitation and the grantee institutions are required to provide $2 in matching funds for every $1 of NYFIRST program assistance. Scientific talent recruited or retained must demonstrate a history of translational research and be actively pursuing research on an innovative solution for an unmet clinical need. The researcher is also required to demonstrate a clear path to commercialization with the potential for significant life sciences economic development benefits in New York State, such as increased patent applications and patentable discoveries, increased recruitment/retention of medical school faculty focused on translational research, or an increase in the number of life sciences jobs created or retained.
“Life sciences is a critical and growing industry in New York State, and each of these institutions are reflective of the phenomenal talent, research and applied knowledge that have thrived here,” Governor Cuomo said. “I congratulate the recipients of the NYFIRST medical school grants and look forward to seeing them further bolster the budding life sciences industry in the Empire State.”
About the Mount Sinai Health System
Mount Sinai Health System is one of the nation’s leading integrated academic health systems and one of the largest in the New York metropolitan area. The Health System includes approximately 48,000 employees, more than 9,000 physicians, and 8,600 nurses across seven hospitals, more than 400 outpatient practices, over 600 research and clinical laboratories, a school of nursing, and schools of medicine and graduate school of biomedical sciences.
As a leading learning health system, Mount Sinai combines clinical expertise with scientific discovery to improve patient care while training the next generation of health care and biomedical leaders. The Health System provides care across every stage of life, from prenatal care through geriatrics, while advancing personalized medicine through artificial intelligence, data science, and biomedical research.
Mount Sinai is consistently recognized among the nation’s leading academic health systems for patient care, research, and education. The Mount Sinai Hospital is ranked No. 1 in New York and recognized as one of the world’s top Smart Hospital by Newsweek. The Icahn School of Medicine at Mount Sinai ranks No. 11 among U.S. medical schools for National Institutes of Health (NIH) funding and No. 1 among freestanding medical schools, reflecting the strength of its scientific enterprise and leadership in biomedical research.
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