Mount Sinai Neuroscientist Chosen as 2018 Pew Scholar by Pew Charitable Trusts
Scholarship provides resources for advancing exploration of fundamental biomedical questions
Erin L. Rich, MD, PhD, Assistant Professor in the Department of Neuroscience at the Icahn School of Medicine at Mount Sinai, was one of 22 early-career researchers to be chosen as a 2018 Pew scholar in biomedical sciences. This prestigious award provides Dr. Rich with a four-year grant to advance her exploration of the biological mechanisms underpinning human health and disease.
“The Pew scholar award is an extremely prestigious honor given to young researchers who demonstrate outstanding promise in biomedical research,” says Eric J. Nestler, MD, PhD, Dean for Academic and Scientific Affairs, Director of The Friedman Brain Institute, and Nash Family Professor of Neuroscience at the Icahn School of Medicine at Mount Sinai. “By bridging basic brain science with computational techniques to help uncover the cellular and circuit basis of motivation and decision-making, Dr. Rich has shown the creativity and innovation that Pew scholars embody. We are grateful to The Pew Charitable Trusts for recognizing her exceptional potential and providing crucial support for her scientific endeavors.”
The 2018 Pew scholars, all of whom have held assistant professor positions for three years or less, will receive four-year grants to advance their explorations. Selected from 184 nominations submitted by leading academic or research institutions across the United States, the 2018 awardees enter a vibrant community of researchers who have received awards from Pew since 1985. Current scholars meet annually to discuss their research, and exchange ideas with peers in fields outside their own.
Dr. Rich received a doctorate in neuroscience in 2008 from the Icahn School of Medicine at Mount Sinai and went on to complete her medical degree and postdoctoral training at the University of California, Berkeley. In 2017, Dr. Rich returned to Mount Sinai as an assistant professor in the Department of Neuroscience.
Dr. Rich’s lab is exploring how the brain uses expectations to motivate behavior, and how it adjusts those expectations when situations change. Expectations, which are based on past experience, color how we perceive and interact with the world. Producing and acting on such predictions requires a coordinated interplay among a number of brain regions, including those involved in perception, memory, and cognition. To study these networks, Dr. Rich’s lab has studied reward-seeking behaviors influenced by the expectation of receiving an incentive. Using a combination of cutting-edge computational and neurophysiological techniques, her team is investigating how the neural activity in a network of key brain areas changes when the research subject seeks one outcome but receives another. Specifically, they will assess the role that emotional-processing centers play in expectations that erroneously guide reward seeking, and how brain networks allow the new, conflicting information to override previous expectations. This work could provide novel insights into disorders that involve inappropriate or inflexible expectations such as anxiety, depression, and substance abuse, paving the way for novel circuit-modulating therapeutics.
“These scientists have shown the boldness and creativity that drives great discoveries, and Pew’s unrestricted support will help them follow the facts wherever they lead,” says Rebecca W. Rimel, president and CEO of The Pew Charitable Trusts. “We’re proud to invest in this gifted group at a pivotal stage in their careers when funds to pursue new concepts and methods can be scarce.”
“I am honored to have been chosen amongst a group of such esteemed fellow researchers and will be forever grateful to Pew for their support to help me continue the work I am so passionate about,” says Dr. Rich. “I look forward to working closely with the other 2018 scholars and members of the Pew community.”
Visit the 2018 Pew Scholars program page to read the scholars’ full abstracts and learn more about the program.
About the Mount Sinai Health System
The Mount Sinai Health System is New York City's largest integrated delivery system encompassing seven hospital campuses, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region. Mount Sinai's vision is to produce the safest care, the highest quality, the highest satisfaction, the best access and the best value of any health system in the nation. The System includes approximately 6,600 primary and specialty care physicians; 10 joint-venture ambulatory surgery centers; more than 140 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers. The Icahn School of Medicine is one of three medical schools that have earned distinction by multiple indicators: ranked in the top 20 by U.S. News & World Report's "Best Medical Schools", aligned with a U.S. News & World Report's "Honor Roll" Hospital, No. 13 in the nation for National Institutes of Health funding, and among the top 10 most innovative research institutions as ranked by the journal Nature in its Nature Innovation Index. This reflects a special level of excellence in education, clinical practice, and research. The Mount Sinai Hospital is ranked No. 18 on U.S. News & World Report's "Honor Roll" of top U.S. hospitals; it is one of the nation's top 20 hospitals in Cardiology/Heart Surgery, Gastroenterology/GI Surgery, Geriatrics, Nephrology, and Neurology/Neurosurgery, and in the top 50 in six other specialties in the 2018-2019 "Best Hospitals" issue. Mount Sinai's Kravis Children's Hospital also is ranked nationally in five out of ten pediatric specialties by U.S. News & World Report. The New York Eye and Ear Infirmary of Mount Sinai is ranked 11th nationally for Ophthalmology and 44th for Ear, Nose, and Throat, while Mount Sinai Beth Israel, Mount Sinai St. Luke's and Mount Sinai West are ranked regionally.