• Press Release

Cigarette Smokers More at Risk for Tobacco Dependence Than Users of Smokeless Tobacco or Multiple Tobacco Products

Findings can help tailor smoking interventions and cessation programs

  • New York, NY
  • (July 27, 2023)

Cigarette smokers have higher odds of tobacco dependence than those who vape or use a variety of types of tobacco products, according to a Mount Sinai study published in July in Nicotine & Tobacco Research.

The findings suggest that tailored tobacco cessation programs are needed for people with different tobacco use habits. The researchers identified three clear types of tobacco users: those who predominantly smoke cigarettes, those who predominantly use smokeless tobacco, and those who predominantly use a combination of cigarettes, e-cigarettes, and cigars.

This discovery is important for tailoring tobacco use reduction and cessation programs to have better success. For example, people who mostly smoke cigarettes would be best served by focusing efforts on reducing their tobacco dependence, while others would be best helped with interventions that increase their likelihood of quitting tobacco use by preventing them from transitioning to only, or predominantly, smoking cigarettes, in addition to outright quitting. 

“With the evolving landscape of tobacco product varieties, our findings are important because it is imperative that we understand which types of tobacco uses lead to dependency, informing cessation program designs and increasing their success,” said the study’s senior author, Bian Liu, PhD, Associate Professor of Population Health Science and Policy at the Icahn School of Medicine at Mount Sinai and member of the Institute for Translational Epidemiology and The Tisch Cancer Institute of the Tisch Cancer Center at Mount Sinai.

Given the increasing availability of diverse tobacco products, many individuals are likely to use multiple tobacco products and to engage in product switch and substitution. This has complicated tobacco cessation efforts aimed at reducing the health burden and economic costs associated with tobacco use and dependence. The lack of research in this area highlighted the need to use novel approaches and richer sources of information, such as that from the Population Assessment of Tobacco and Health (PATH) study, to explore and understand tobacco use and tobacco dependence profiles.

In this study, Mount Sinai researchers examined tobacco use profiles across four PATH surveys from 2013 to 2018. The scientists identified tobacco use profiles through intricate analysis and investigated the longitudinal association between tobacco use and dependency, identifying the subgroups with a high risk of dependency.

“As individuals may change their habits over time, future studies should examine patterns of tobacco use changes, including whether people’s changing habits differ by sociodemographic factors, and we should investigate how these changes impact tobacco dependency over time in the context of other smoking behaviors, including attempting to quit, relapse, and smoking cessation,” said the study’s first author, Lihua Li, PhD, Associate Professor of Population Health Science and Policy at Icahn Mount Sinai and member of The Tisch Cancer Institute and Institute for Health Care Delivery Science.


About the Mount Sinai Health System

Mount Sinai Health System is one of the nation’s leading integrated academic health systems and one of the largest in the New York metropolitan area. Its comprehensive system includes seven hospitals, more than 400 outpatient practices, over 600 research and clinical laboratories, the Icahn School of Medicine at Mount Sinai, the Graduate School of Biomedical Sciences, and the Mount Sinai Phillips School of Nursing. Together, the Health System comprises approximately 48,000 employees, more than 9,000 physicians, and 8,600 nurses.

As a leading learning health system, Mount Sinai combines clinical expertise with scientific discovery to improve patient care while training the next generation of health care and biomedical leaders. The Health System provides care across every stage of life, from prenatal care through geriatrics, while advancing personalized medicine through artificial intelligence, data science, and biomedical research.

Mount Sinai is consistently recognized among the nation’s leading academic health systems for patient care, research, and education. The Mount Sinai Hospital is ranked No. 1 in New York by Newsweek and No. 5 on the magazine’s World’s Best Hospitals list. The Icahn School of Medicine at Mount Sinai ranks No. 11 among U.S. medical schools and No. 1 among freestanding medical schools for National Institutes of Health funding, reflecting the strength of its scientific enterprise and leadership in biomedical research.