Mount Sinai Designated as National Cancer Institute Proteogenomics Data Analysis Center
Will generate potential biomarkers and drug targets, and new insights into cancer biology
The Office of Cancer Clinical Proteomics Research at the National Cancer Institute (NCI) has awarded $4.2 million over five years to Mount Sinai researchers establishing a Proteogenomic Data Analysis Center (PGDAC) to advance cancer research and treatments. Proteogenomics, which studies the roles of proteins and genes within a cell or organism, is a crucial area of exploration to further our understanding of cancer.
The award supports the Center’s work to identify potential biomarkers and drug targets for cancer, new insights into cancer biology, and bioinformatics tools to enable more advanced exploration and discovery from cancer-related datasets.
The Center’s lead investigators, Pei Wang, PhD, Professor, Genetic and Genomic Sciences, and Avi Ma’ayan, PhD, Professor, Pharmacological Sciences, and Director of the Mount Sinai Center for Bioinformatics, will leverage their expertise in statistics/biostatistics, machine learning, data integration, systems pharmacology, and proteomics data modeling to further understand the proteogenomic complexity of tumors.
The centers of excellence are part of NCI’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) program, a national effort to advance and accelerate cancer research through the application of proteogenomics. Mount Sinai is one of 14 CPTAC centers nationwide.
Data generated and tools developed by the CPTAC centers will be made available to the public to help further advance and accelerate cancer research.
Who: Pei Wang, PhD, Professor, Genetic and Genomic Sciences; Avi Ma’ayan, PhD, Professor, Pharmacological Sciences and Director of the Mount Sinai Center for Bioinformatics
NCI Announcement: https://proteomics.cancer.gov/news_and_announcements/cptac-announces-new-pcc-pgdac-and-ptrc-teams?cid=eb_govdel
About the Mount Sinai Health System
Mount Sinai Health System is one of the nation’s leading integrated academic health systems and one of the largest in the New York metropolitan area. Its comprehensive system includes seven hospitals, more than 400 outpatient practices, over 600 research and clinical laboratories, the Icahn School of Medicine at Mount Sinai, the Graduate School of Biomedical Sciences, and the Mount Sinai Phillips School of Nursing. Together, the Health System comprises approximately 48,000 employees, more than 9,000 physicians, and 8,600 nurses.
As a leading learning health system, Mount Sinai combines clinical expertise with scientific discovery to improve patient care while training the next generation of health care and biomedical leaders. The Health System provides care across every stage of life, from prenatal care through geriatrics, while advancing personalized medicine through artificial intelligence, data science, and biomedical research.
Mount Sinai is consistently recognized among the nation’s leading academic health systems for patient care, research, and education. The Mount Sinai Hospital is ranked No. 1 in New York by Newsweek and No. 5 on the magazine’s World’s Best Hospitals list. The Icahn School of Medicine at Mount Sinai ranks No. 11 among U.S. medical schools and No. 1 among freestanding medical schools for National Institutes of Health funding, reflecting the strength of its scientific enterprise and leadership in biomedical research.