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"Patients With Exacerbated Asthma Have Unique Nasal Microbiomes" - Carisa D. Brewster

  • MD Magazine
  • New York, NY
  • (September 18, 2018)

Patients with exacerbated asthma have a distinct nasal microbiome from those with controlled asthma and those without an asthma diagnosis, according to a recent study. Although the lower airway microbiome has been frequently studied in asthma, the nasal microbiome has received much less scrutiny, said lead author, Supinda Bunyavanich, MD, MPH, associate professor of genetics and genomic sciences, pediatric allergy and immunology at the Icahn School of Medicine at Mount Sinai. “Given the possible roles for upper airway microbiota in asthma pathobiology, our study fills an important niche in airway microbiome research and ease of airway sampling for monitoring and investigation of asthma,” said Dr. Bunyavanich. “Our findings lend insight into mechanistic considerations about host and microbiome interactions in asthma,” added Dr. Bunyavanich. “This may enable the development of nasal microbial markers of asthma for detection and disease monitoring.”

- Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai

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