"Critical Cancer Immunity Genes Identified Using New Genetic Barcoding Technology"
Scientists at Mount Sinai have developed a novel technology for simultaneously analyzing the functions of hundreds of genes with resolution reaching the single cell level. The technology relies on a barcoding approach using a novel protein described in a paper published in the journal Cell. "There is still a great deal of work to be done to fully understand the human genome. We still don't know what most genes do and how they are connected," said Brian Brown, PhD, associate professor of genetics and genomic sciences and associate director of the Immunology Institute at the Icahn School of Medicine at Mount Sinai and senior author of the publication. "The Pro-Code technology could greatly accelerate one of the major goals of the post-genome era: annotation of the human genome. This discovery will be key to discover disease-causing genes that could lead to novel drug targets. It's already given us new insights in cancer immunology."
- Brian Brown, PhD, Associate Professor, Genetics and Genomic Sciences, Associate Director, Immunology Institute, Icahn School of Medicine at Mount Sinai