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Brian D Brown, PhD Email Brian Brown

    • Position
    • PROFESSOR | Genetics and Genomic Sciences
    • Language
    • English

Dr. Brian Brown is broadly trained in molecular and cellular biology with a strong focus on immunology and translational medicine. His training began with his doctoral studies in Canada and his work to establish ways to overcome the immune response hindering gene therapy. He subsequently did his postdoctoral studies in Italy where he helped develop a new platform for controlling gene expression, which has led to improvements in experimental treatments for genetic disease, cancer, and viral infection. Dr. Brown's lab is now working to identify the factors that control immunity and tolerance, and translate these findings in to strategies that can be used to turn the immune system against cancer.  In 2008 Dr. Brown joined the faculty of Mount Sinai as an Assistant Professor and he was promoted to Associate Professor in 2013.  In 2016 he becamse the Associate Director of Mount Sinai's Immunology Institute. 

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Research Topics

Antigen Presentation, Autoimmunity, Cancer, Cellular Immunity, Dendritic Cells, Gene Discovery, Gene Expressions, Gene Regulation, Gene Therapy, Gene editing, Genomics, Immunological Tolerance, Immunology, Inflammation, Macrophage, Molecular Biology, RNA, RNA Splicing & Processing, Stem Cells, T Cells, Tolerance, Transcriptional Activation and Repression

Multi-Disciplinary Training Areas

Genetics and Data Science [GDS], Immunology [IMM]


BSc, University of Guelph

Fellowship, San Raffaele Scientific Institute

PhD, Queen's University