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"Early-Onset Atopic Dermatitis Phenotypes Differ Between Children, Adults" - Katherine Bortz

  • Healio
  • New York, NY
  • (May 24, 2018)

The skin of children with early-onset atopic dermatitis exhibits significantly different phenotypes when compared with the skin of adults with a long-standing history with the disease, according to research published in The Journal of Allergy and Clinical Immunology. “It is important to recognize the differences in phenotypes between children and adults because different or additional therapeutics may be more suited to children or adults,” said Emma Guttman-Yassky, MD, PhD, the director of the center of excellence in eczema and professor of dermatology at the Icahn School of Medicine at Mount Sinai. “While the TH2 axis is activated in both children and adults, the TH17 axis is increased primarily in children, similar to psoriasis. Perhaps psoriasis-focused treatments can be applicable to children with atopic dermatitis.”

- Emma Guttman-Yassky, MD, PhD, The Sol & Clara Professor, Dermatology, Clinical Immunology, Medicine, Vice Chair, Research, Department of Dermatology, Director, The Center for Excellence in Eczema, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai

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