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"Can Anticoagulants Prevent Alzheimer's?" - Megan Brooks

  • Medscape
  • New York, NY
  • (October 11, 2019)

Treatment with an oral anticoagulant delays memory decline and the conversion to Alzheimer disease in mice, according to research performed by senior investigator Valentin Fuster, MD, PhD, director of Mount Sinai Heart and physician-in-chief of The Mount Sinai Hospital. Dr. Fuster’s study was published online in the Journal of the American College of Cardiology. The finding should spark future studies to see whether use of direct oral anticoagulants has therapeutic value in AD. According to Dr. Fuster, “Dr Alois Alzheimer already more than a century ago said that this disease was a disease of the blood vessels of the brain, and this was forgotten over many years.” He added, “We began to study this with the most modern technology in a mouse model of Alzheimer's that is very similar to humans.”

— Valentin Fuster, MD, PhD, Director, Mount Sinai Heart, Physician in Chief, The Mount Sinai Hospital, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai

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