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"Switching Antipsychotics Doesn’t Improve Schizophrenia, Study Suggests" - Megan Thielking

  • STAT: Morning Rounds
  • New York, NY
  • (August 14, 2018)

Patients with schizophrenia are often switched to a new kind of antipsychotic if they don’t respond to the first type of treatment – but a new analysis suggests that doesn’t help. Researchers at the Icahn School of Medicine at Mount Sinai ran a randomized trial with 446 patients being treated with amisulpride for schizophrenia. Patients switched to a new drug after a month weren’t any more likely to see improved outcomes than patients who stayed on the first drug. The authors say that suggests it’s not necessary to try another antipsychotic before switching to more aggressive treatment, which could potentially improve outcomes earlier.

- Rene S. Kahn, MD, PhD, Esther and Joseph Klingenstein Professor, System Chair, Psychiatry, Icahn School of Medicine at Mount Sinai

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