"Diverting Contrast No Help For AKI After Coronary Angiography" - Nicole Lou
Despite success in cutting down on contrast media volume, the Avert system didn't reduce the risk of acute kidney injury (AKI) after coronary angiography, a trial found. Operators used 85.6 mL of contrast when patients were randomized to hydration plus manual contrast injection with the contrast modulation system (versus 101.3 mL with hydration alone, P=0.02), and 114 mL in the subset of percutaneous coronary intervention (PCI) recipients (versus 147 mL with hydration alone, P=0.001), according Roxana Mehran, MD, professor of medicine, cardiology, and director of Interventional Cardiovascular Research and Clinical Trials at the Zena and Michael A. Weiner Cardiovascular Institute at the Icahn School of Medicine at Mount Sinai. Avert is a device that diverts contrast during coronary injection; the amount of contrast medium sent away depends on injection force and the setting selected on the contrast modulator. Dr. Mehran's group noted that having most patients undergo diagnostic procedures only could have reduced their power to show a difference in contrast-induced AKI between groups.
- Roxana Mehran, MD, Professor, Medicine, Cardiology, Population Health Science and Policy, Director, Interventional Cardiovascular Research and Clinical Trials, Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of Medicine at Mount Sinai
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Healio: Cardiology Today