Genome Web - "Expression Study Yields Potential Marker for Huntington Disease Activity, Drug Response"

 – October 4, 2011 /Press Release/  –– 

A gene coding for a histone protein involved in chromatin plasticity is found at elevated levels in blood samples from those with Huntington disease, according to a study in the early, online edition of the Proceedings of the National Academy of Sciences. An American research team assessed gene expression patterns in blood samples from 119 individuals with or without Huntington disease, reasoning that they might find detectable expression shifts — even outside of the tissues that undergo characteristic neurodegeneration during Huntington disease. Learn more.