Mount Sinai has a unique and rich tradition of individualized treatment, scientific research, and discovery in ulcerative colitis. The physicians and scientists in the Mount Sinai Health System are constantly conducting clinical trials and are developing new therapies to help patients manage their disease.

Ulcerative colitis, a type of inflammatory bowel disease (IBD), causes inflammation in the large intestine or colon. The innermost lining of the colon becomes inflamed and develops tiny open sores, or ulcers, that produce mucous and bleed. Ulcerative colitis can cause a variety of symptoms—including chronic diarrhea that may or may not go into periods of remission, blood in the stool, mild to severe abdominal pain, fatigue, and malnutrition—and can have a major impact on quality of life.

Ulcerative colitis is a progressive disease that over time can lead to bowel damage and complications including abnormal colon contraction and absorption, colon cancer, and surgery.

While the cause of IBD is still unknown, it involves the interplay of genetic predisposition, an abnormal immune system response, and environmental factors.

Below are some symptoms:

• Persistent diarrhea and rectal bleeding
• Urgent need to move bowels
• Abdominal cramping and pain
• Constipation
• Fever
• Appetite and Weight Loss
• Fatigue

Please note: only proper testing performed by your doctor can diagnose ulcerative colitis.