Current Studies

The Pediatric Mood and Anxiety Disorders Program’s current research studies include the following investigations.

Actively Recruiting

The Neuroimmunology of Anhedonia examines the neurobiology of anhedonia—the reduced capacity to experience pleasure—in adolescents with major depressive disorder (MDD) and healthy controls through immunological and neurochemical investigative approaches. The study involves a brief phone screen for eligibility, as well as two study visits: 1) Includes a baseline diagnostic evaluation; 2) Involves a blood draw and magnetic resonance spectroscopy (MRS) brain scan and/or electroencephalogram (EEG) . We are recruiting both healthy and depressed adolescents, between the ages of 12 and 18, who are psychotropic medication-free. This study is sponsored by the National Institute of Mental Health.

Neuroinflammation and Positive Valence System (PVS) Deficits in Adolescents examines the neuroimmunology of specific reward processes in adolescents through immunological, functional magnetic resonance imaging (fMRI), and magnetic resonance spectroscopy (MRS) approaches. Specifically, we focus on Reward Expectancy versus Initial Responsiveness to Reward Attainment, reflecting reward anticipation and receipt. The study involves a brief phone screen for eligibility, as well as two study visits: 1) Includes a baseline diagnostic evaluation; 2) Involves a blood draw before and after a social stress test, as well as a brain scan including fMRI and MRS. We are recruiting both healthy adolescents and adolescents displaying any psychiatric symptoms, between the ages 12 to 18, who are psychotropic-medication free. This study is sponsored by the National Institute of Mental Health.

For more information regarding our studies or participating in a study, please contact clinical research coordinator Lushna Mehra (212-659-1673; lushna.mehra@mssm.edu)

Contact Us

Clinical Division and General Info
Melissa Fluehr
Tel: 212-659-1660
E-mail: melissa.fluehr@mssm.eduu

Research Division
Rachel Freed
Tel: 212-659-1662
E-mail: rachel.freed@mssm.edu