Clinical Trials

The Icahn School of Medicine at Mount Sinai, Department of Dermatology, is a leader in developing and testing advanced skin therapies. As part of our research, we participate in these clinical trials.  We seek patients who would like to enroll in a number of our cutting edge clinical trials.

Platelet-Rich Plasma for Hair Loss in Women

We are evaluating the efficacy of platelet-rich plasma (PRP) in treating non-scarring hair loss in women. PRP uses your own body’s healing ability to stimulate skin recovery and boost collagen production. For this procedure, we draw your blood and place it in a centrifuge to isolate the platelets. Then we inject your own platelets into your scalp. Participating in the study involves:

  • Coming to our site seven times over a period of six months
  • A scalp biopsy
  • Permission to photograph your scalp
  • This study has a placebo group

To participate, you must be a female between ages 18 and 65. You must be able to provide consent and adhere to scheduled visits. You are not eligible if you are currently or have been in the past six months on a topical treatment (such as minoxidil, prostaglandin analogues, retinoids, and corticosteroids), on any type of hormonal therapy, on a systemic medication (such as finasteride, dutasteride, spironolactone or antiandrogens), are prone to keloids, or have anemia, Vitamin D deficiency, thyroid disease, or are immunosuppressed.

Bellafill® for Hand Wrinkles

In this study we evaluate the effectiveness of Bellafill® for treating hand wrinkles. Bellafill® is a semi-permanent filler comprised of polymethyl-methacrylate microspheres, which come from bovine collagen. Results with Bellafill® can last up to five years.

To participate, you must be a female between ages 18 and 65. You must be able to provide consent and adhere to scheduled visits. You are not eligible if you are allergic to bovine collagen or have a connective tissue disease.

Botulinum Toxin for Minimizing Post-Excisional Scarring

We are looking at whether botulinum toxin helps prevent excessive scarring after surgery. This study requires follow-up over 24 weeks. We will inject your forehead with either botulinum toxin or a placebo.

You can participate in this study if you are over 18 years of age and are scheduled for an excision of forehead skin. We will need to follow you over a 24-week period. If you are pregnant or lactating, have a neuromuscular disorder (such as myasthenia gravis or Lambert-Eaton syndrome), or a history of keloid scarring, you are not qualified.

Fractional CO2 Laser Resurfacing for Post-Surgical Scarring

In this study, we are looking at the benefits of using ablative fractionated CO2 laser to improve surgical scars. We are researching when to perform these laser treatments for the best results. The study involves treatment of the scar with a laser and follow-up over 24 weeks. We will take a biopsy of the scar at 24 weeks.

You are eligible to participate if you are over 18 years old, undergoing surgical excision on the arms or legs, and are willing to have us check you in 24 months. We cannot include you if you have undergone a laser treatment to the affected site over the past year, have a history of keloids, or have received isotretinoin (Accutane) treatment in the past six months.