A Communication Tool to Assist Older Adults Facing Dialysis Choices
The purpose of this study is to test the effect of the "Best Case/Worse Case" (BC/WC) communication tool on receipt of palliative care and intensity of treatment at the end of life, quality of life, and quality of communication for older patients with end-stage renal di...
Age: 60 years - 66+
Gender: All
XIENCE 28 USA Study
The XIENCE 28 USA Study is prospective, single arm, multi-center, open label, non-randomized trial to evaluate safety of 1-month (as short as 28 days) dual antiplatelet therapy (DAPT) in subjects at high risk of bleeding (HBR) undergoing percutaneous coronary interventi...
Age: 18 - 100 years
Gender: All
A Study of Pevonedistat in Combination With Azacitidine in Participants With Higher-risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myelogenous Leukemia (AML) With Severe Renal Impairment or Mild Hepatic Impairment
The purpose of this study is to characterize the pharmacokinetic (PK) of pevonedistat in
participants with severe renal impairment and mild hepatic impairment.
Age: 18 years - 66+
Gender: All
A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)
Primary Objectives:
To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric
CKD subjects with iron deficiency anemia (IDA) or who are at risk of development of IDA
Secondary Objective:
To determine the single-dose pharmacokinetics ...
Age: 2 - 17 years
Gender: All
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation
and to improve the safety of living kidney donation based upon variation in the
apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye
co...
Age: Birth - 66+
Gender: All
World Trade Center Kidney-Link
This study focuses on the prevalence and identification of kidney disease among participants
of the WTC Health Program and the study team are planning to assess kidney disease in a
multi-factorial manner. The first aim of this study is to correlate kidney dysfunction ...
Age: 18 - 75 years
Gender: All
A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease
This parallel-group, randomized, placebo-controlled study will examine the incidence and
severity of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) stage
III/IV following an i.v. injection of iso-osmolar iodinated contrast material iodixanol
...
Age: 18 years - 66+
Gender: All