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Improving Medication Management in World Trade Center Responders

By 2030, the majority of World Trade Center (WTC) rescue and recovery workers (responders) will be aged 65 and over and at risk for aging-related conditions and consequences including the concurrent use of five or more medications (i.e., polypharmacy). The purpose of...

Age: 50 years - 66+

Gender: All

Acute Migraine Treatment in the ED With Gepants

This study evaluates the effectiveness of rimegepant 75 mg orally disintegrating tablet (ODT) single-dose or zavegepant 10 mg nasal spray single-dose as acute migraine treatments during Emergency Department (ED) encounters. Although these two calcitonin gene-related pep...

Age: 18 years - 66+

Gender: All

SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)

Robotic-assisted radical prostatectomy (RALP) has become the standard of care in the management of localized prostate cancer. However, post-prostatectomy erectile dysfunction (ED) and urinary incontinence still pose a challenge that adversely affects the patient's qu...

Age: 18 years - 66+

Gender: Male

Adjunctive Cannabidiol for Recovery From Opioid Study

The long-term goal of the project is to determine whether cannabidiol (CBD) can reduce craving and relapse in individuals with opioid use disorder (OUD). The first phase of this project was an open cross-over design study in healthy individuals to confirm the safety and...

Age: 18 - 65 years

Gender: All

MAGIC Ruxolitinib for aGVHD

This clinical trial will study ruxolitinib-based treatment of acute graft-versus-host-disease (GVHD) that developed following allogeneic hematopoietic cell transplant. Acute GVHD occurs when donor cells attack the healthy tissue of the body. The most common symptoms ...

Age: 18 years - 66+

Gender: All

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

This real-world, international registry aims to evaluate the current experience with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in adult congenital heart disease (ACHD) patients by investigating the prescription patterns, safety, tolerability, and potential b...

Parent-Child EF Intervention

Koronis Biomedical Technologies Corporation (KBT) is developing a cognitive intervention to promote healthy development of Executive Function (EF) skills in young children by leveraging a smartphone-based training regime designed for parents.

Age: 2 - 5 years

Gender: All

Human Milk Research Study

What is the purpose of the study? The maternal RSV vaccine was licensed in 2023 for prevention of RSV-associated lower respiratory tract disease in infants up to six months of age. Maternal immunization protects infants via antibodies transferred in utero. Additional be...

Age: 18 - 50 years

Gender: Female