The Safety of Immunosuppression in A Prospective Cohort of Inflammatory Bowel Disease Patients With a HIstoRy of CancEr (SAPPHIRE): A National Study
What Is SAPPHIRE?
Inflammatory bowel disease (IBD) is a condition in which the body’s immune system reacts inappropriately and causes ongoing inflammation in the digestive tract. To manage this, many patients are often treated with immunosuppressants. Beca...
A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation
This is a study assessing the feasibility of performing an anti-aging intervention which
is a combination of an exercise regimen, spermidine supplementation, and either rapamycin
or lamivudine.
Age: 65 - 80 years
Gender: All
A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation
This is a study assessing the feasibility of performing an anti-aging intervention which
is a combination of an exercise regimen, spermidine supplementation, and either rapamycin
or lamivudine.
Age: 65 - 80 years
Gender: All
Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease
The purpose of this research study is to evaluate what type of treatment will be
beneficial for people with Crohn's disease and difficult to treat inflammation in the
small bowel. Current therapies are used to control the inflammation due to Crohn's
disease in your d...
Age: 18 - 80 years
Gender: All
Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease
The purpose of this research study is to evaluate what type of treatment will be beneficial for people with Crohn's disease and difficult to treat inflammation in the small bowel. Current therapies are used to control the inflammation due to Crohn's disease in your dige...
Age: 18 - 80 years
Gender: All
A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
CIDP is an autoimmune disease. This means that the body's germ fighting (immune) system
attacks itself. In CIDP, the immune system attacks the protective covering around the
nerves called myelin. Over time, these nerves lose their ability to send signals to the
muscl...
Age: 18 years - 66+
Gender: All
Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous Urticaria
The purpose of this research study is to see if a drug called ritlecitinib is safe and
effective for treating chronic spontaneous urticaria (CSU). CSU is hives and itching
lasting over six weeks. Ritlecitinib is approved by the Food and Drug Administration
(FDA) to t...
Age: 18 - 65 years
Gender: All
Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous Urticaria
The purpose of this research study is to see if a drug called ritlecitinib is safe and
effective for treating chronic spontaneous urticaria (CSU). CSU is hives and itching
lasting over six weeks. Ritlecitinib is approved by the Food and Drug Administration
(FDA) to t...
Age: 18 - 65 years
Gender: All
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most frequently affecting the bowels. It can cause
many different symptoms including belly pain, diarrhea, tiredness, and weight loss.
Treatmen...
Age: 18 - 75 years
Gender: All
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most frequently affecting the bowels. It can cause
many different symptoms including belly pain, diarrhea, tiredness, and weight loss.
Treatmen...
Age: 18 - 75 years
Gender: All
Longitudinal Monitoring of Inflammatory Bowel Disease Using a Sweat Sensing Wearable Device (Sweat Sensor Study)
The Sweat Sensor Study at Mount Sinai aims to measure and monitor markers of inflammation and the immune system, such as C-reactive protein and calprotectin, continuously in the sweat using a wearable sweat sensing device. Our hope is that this wearable device will even...
Age: 18 years - 66+
Gender: All
Bimekizumab in Plaque Psoriasis
The purpose of this research study is to evaluate the effectiveness and safety of
bimekizumab in individuals with moderate-to-severe psoriasis who have failed similar
therapies. Bimekizumab improves psoriasis by suppressing a type of substance found in
bodies called ...
Age: 18 years - 66+
Gender: All
Bimekizumab in Plaque Psoriasis
The purpose of this research study is to evaluate the effectiveness and safety of
bimekizumab in individuals with moderate-to-severe psoriasis who have failed similar
therapies. Bimekizumab improves psoriasis by suppressing a type of substance found in
bodies called ...
Age: 18 years - 66+
Gender: All
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most often affecting the bowels. It can cause many
different symptoms including abdominal pain, diarrhea, tiredness, and weight loss. This
stud...
Age: 2 - 17 years
Gender: All
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most often affecting the bowels. It can cause many
different symptoms including abdominal pain, diarrhea, tiredness, and weight loss. This
stud...
Age: 2 - 17 years
Gender: All
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any
part of the gut. The purpose of this study is to evaluate the efficacy and safety of
TAK-279 versus placebo in participants with moderately to severely active Crohn's disease
(C...
Age: 18 - 75 years
Gender: All
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any
part of the gut. The purpose of this study is to evaluate the efficacy and safety of
TAK-279 versus placebo in participants with moderately to severely active Crohn's disease
(C...
Age: 18 - 75 years
Gender: All
Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation
The PLANET Study aims to determine the impact of microplastics on intestinal inflammation
and gut microbiome in order to understand the role of this pollutant on the risk of
developing inflammatory bowel disease (IBD) as well as other diseases. With this
information,...
Age: 18 years - 66+
Gender: All
Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation
The PLANET Study aims to determine the impact of microplastics on intestinal inflammation
and gut microbiome in order to understand the role of this pollutant on the risk of
developing inflammatory bowel disease (IBD) as well as other diseases. With this
information,...
Age: 18 years - 66+
Gender: All
A Trial to Learn if Dupilumab is Safe for and Helps Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis
The study is researching an experimental drug called dupilumab. The study is focused on
participants with active eosinophilic gastritis (EoG) with or without eosinophilic
duodenitis (EoD). Participants with EoD only are not eligible for enrollment. EoG and EoD
are un...
Age: 12 years - 66+
Gender: All