Longitudinal Monitoring of Inflammatory Bowel Disease Using a Sweat Sensing Wearable Device (Sweat Sensor Study)
The Sweat Sensor Study at Mount Sinai aims to measure and monitor markers of inflammation and the immune system, such as C-reactive protein and calprotectin, continuously in the sweat using a wearable sweat sensing device. Our hope is that this wearable device will even...
Age: 18 years - 66+
Gender: All
Bimekizumab in Plaque Psoriasis
The purpose of this research study is to evaluate the effectiveness and safety of
bimekizumab in individuals with moderate-to-severe psoriasis who have failed similar
therapies. Bimekizumab improves psoriasis by suppressing a type of substance found in
bodies called ...
Age: 18 years - 66+
Gender: All
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any
part of the gut. The purpose of this study is to evaluate the efficacy and safety of
TAK-279 versus placebo in participants with moderately to severely active Crohn's disease
(C...
Age: 18 - 75 years
Gender: All
Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation
The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and
gut microbiome in order to understand the role of this pollutant on the risk of developing
inflammatory bowel disease (IBD) as well as other diseases. With this information...
Age: 18 years - 66+
Gender: All
A Trial to Learn if Dupilumab is Safe for and Helps Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis
The study is researching an experimental drug called dupilumab. The study is focused on
participants with active eosinophilic gastritis (EoG) with or without eosinophilic
duodenitis (EoD). Participants with EoD only are not eligible for enrollment. EoG and EoD
are un...
Age: 12 years - 66+
Gender: All
The Ambient Light Multiple Myeloma Study
The aim of this multi-site randomized control trial will be is to assess the impact
Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and
Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell
Transplantat...
Age: 21 years - 66+
Gender: All
RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptoms
This study is a platform protocol designed to be flexible so that it is suitable for a
wide range of settings within health care systems and in community settings where it can
be integrated into COVID-19 programs and subsequent treatment plans. This protocol is a
pro...
Age: 18 years - 66+
Gender: All
Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain
A randomized, double blind, study of dronabinol as a palliative agent in the treatment of
pain, inflammation, and other complications of sickle cell disease (SCD).
Age: 18 years - 66+
Gender: All
Renal Allograft Fibrosis Study
Despite the reduction in acute rejection episodes in renal transplant patients due to
modern immunosuppression, proportionate improvements in long-term allograft survival have
not been achieved. Virtually any disease or injury affecting renal allografts can
culminate...
Age: 18 years - 66+
Gender: All
Study to Evaluate Safety, Tolerability and Efficacy of Oral E-B-FAHF-2 in Mild-to-Moderate Crohn's Disease
Crohn's disease (CD) is the major form of inflammatory bowel disease (IBD) affecting adults.
It is a life-long disease characterized by chronic and relapsing inflammation of the
gastrointestinal tract. CD has multiple clinical phenotypes and disease severities that
...
Age: 18 - 30 years
Gender: All
Modulating Early Life Microbiome Through Dietary Intervention in Crohn's Disease
The MELODY Trial: Modulating Early Life Microbiome through Dietary Intervention in Crohn's
Disease, will test whether a non-invasive dietary intervention during pregnancy can improve
the gut microbiota composition in both pregnant Crohn's disease patients and their ...
Age: 18 years - 66+
Gender: Female
A Double-Masked, Placebo-Controlled, Randomized, Phase II Clinical Trial To Assess The Efficacy Of SCH1 In The Treatment Of Acute Infectious Conjunctivitis
Acute infectious conjunctivitis is a leading cause of ocular morbidity, epidemic eye infection, lost productivity, patient discomfort and in some cases permanent visual compromise. The infectious agent is frequently viral in origin and frequently bacterial in origin wit...
Age: 18 - 90 years
Gender: All
Light and the Effect on Metabolic Syndrome and Alzheimer's Disease
This study's main hypothesis is that a delivering a tailored lighting intervention (TLI) will
provide a successful means for promoting circadian entrainment and treating metabolic disease
and inflammation in patients with mild cognitive impairment (MCI) and Alzheime...
Age: 55 years - 66+
Gender: All
An open-label pilot study to investigate the efficacy of apremilast in the treatment of central centrifugal cicatricial alopecia (CCCA)
"The purpose of this study is to see if the use of apremilast has an effect on the symptoms and progression of central centrifugal cicatricial alopecia (CCCA). Apremilast is an oral PDE4 inhibitor that has anti-inflammatory properties. It inhibits several substances inv...
Age: 18 years - 66+
Gender: Female
Autologous Stem Cell Transplant for Crohn's Disease
Crohn's Disease (CD) is an inflammatory bowel disease. It can lead to significant
complications and discomfort in the stomach and intestines. Crohn's disease is a
debilitating, incurable disease of immune cells; it affects almost 1 million people in the
United Sta...
Age: 18 years - 66+
Gender: All
Pancreas Registry and High Risk Registry
The purpose of this study is to establish a registry of patients with pancreatic diseases.
Patients included in the registry may include those with: pancreatic cancer, precancerous
lesions of the pancreas, inflammatory lesions of the pancreas, cystic lesions of the
...
Age: 18 years - 66+
Gender: All