Assessment of Supportive Care and Educational Needs to Guide Quality Care Improvements for Patients With Locally Advanced and Metastatic Bladder Cancer
The overall goal of this study is to facilitate care improvements for bladder cancer patients with locally advanced or metastatic disease by designing and evaluating a patient need assessment screening tool to be used, in the future, as standard screening measure. Adult...
Age: 18 - 89 years
Gender: All
Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer
Black and Latina women experience disparities in supportive and palliative care access and
outcomes. The goal of the proposed pilot study is to evaluate the feasibility and
acceptability of a community navigator delivered supportive care intervention for
historica...
Age: 18 years - 66+
Gender: Female
Intratumoral and Systemic Hiltonol® (Poly-ICLC) in Prostate Cancer Patients on Active Surveillance
This is a partially blinded randomized controlled phase II pilot study comparing Poly-ICLC (Hiltonol®) treatment vs no treatment, for prostate cancer participants on active surveillance.
Age: 18 years - 66+
Gender: Male
Precision Medicine Study
This will be a 2 year study to evaluate and improve cancer sequencing as applied to the
characterization of tumor molecular make-up and the identification of novel therapeutics
(n=100). Participants who will undergo tumor biopsy for management of multiple myeloma
(MM...
Age: 18 years - 66+
Gender: All
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
This study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of
INCB160058 in Participants With Myeloproliferative Neoplasms.
Age: 18 years - 66+
Gender: All
Study of BMS-986393 a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
The purpose of this study is to evaluate the effectiveness and safety of BMS-986393 in
participants with relapsed or refractory multiple myeloma.
Age: 18 years - 66+
Gender: All
Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer
TIER-PC is an adaptive model of delivering palliative care that provides the right level of
care to the right patients at the right time. It represents an adaption of the Mount Sinai
PALLIATIVE CARE AT HOME (PC@H) program, which delivers home-based palliative care. ...
Age: 18 years - 66+
Gender: All
Evaluating the Efficacy of the eNav Toolkit to Improve Colorectal Cancer Screening
The purpose of this research study is to evaluate the efficacy of a digital navigation tool,
called the eNav to improve colorectal cancer screening uptake among patients treated at
federally qualified health centers (FQHC)s. The digital navigation tool includes a we...
Age: 45 - 75 years
Gender: All
A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma
The purpose of this study is to assess BMS-986453 in participants with relapsed and/or
refractory multiple myeloma (RRMM).
Age: 18 years - 66+
Gender: All
Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)
Researchers are looking for new ways to treat people with endometrial cancer (EC) who
have previously received treatment with platinum based therapy (a type of chemotherapy)
and immunotherapy. Immunotherapy is a treatment that helps the immune system fight
cancer. Th...
Age: 18 years - 66+
Gender: Female
A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies
The primary purpose of this study is to assess the safety and tolerability of AB801 in
participants with advanced malignancies, and to determine a recommended AB801 dose for
expansion.
Age: 18 years - 66+
Gender: All
A Study of Sovilnesib in Subjects With Ovarian Cancer
This is a randomized, phase 1b study to assess the safety, tolerability, pharmacokinetics
(PK), and efficacy of sovilnesib at different dose levels to establish the Recommended
Phase 2 Dose (RP2D) of sovilnesib in subjects with high grade serous ovarian cancer
(HGSOC...
Age: 18 years - 66+
Gender: Female
A Study to Evaluate INCA033989 Administered in Participants With Myeloproliferative Neoplasms
This study is being conducted to evaluate the safety, tolerability, dose-limiting toxicity
(DLT) and determine the maximum tolerated dose (MTD) and/or recommended dose(s) for expansion
(RDE) of INCA033989 administered in participants with myeloproliferative neoplasm...
Age: 18 years - 66+
Gender: All
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
This is a first-in-human Phase I, open-label, dose-escalation and expansion study
designed to evaluate the safety, tolerability, pharmacokinetics, immunogenicity,
pharmacodynamic, and preliminary anti-tumor activity of RO7566802 as a single agent and
in combination w...
Age: 18 years - 66+
Gender: All
A Study of hSTC810 in Combination With Paclitaxel in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer
The purpose of this clinical study is to assess the safety and efficacy of hSTC810 and
paclitaxel combination therapy in patients with relapsed or refractory extensive stage small
cell lung cancer.
Age: 18 years - 66+
Gender: All
A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2
This clinical trial is studying advanced or metastatic solid tumors. Once a solid tumor
has grown very large in one spot or has spread to other places in the body, it is called
advanced or metastatic cancer. Participants in this study must have head and neck
squamous...
Age: 18 years - 66+
Gender: All
A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors
This is an open-label, multicenter, and nonrandomized dose escalation and dose expansion
study to evaluate BGB-26808 as monotherapy or in combination with tislelizumab in
participants with advanced solid tumors. The main purpose of this study is to explore the
recomm...
Age: 18 years - 66+
Gender: All
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
This phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in
addition to standard of care chemotherapy versus standard of care chemotherapy alone in
treating patients with colorectal cancer that has spread to the liver (liver metastases)
and c...
Age: 18 years - 66+
Gender: All
A Study of GC012F, a CAR T Therapy Targeting CD19 and BCMA in Subjects With Relapsed/Refractory Multiple Myeloma
This trial is a phase 1b/2, open-label, multicenter study of GC012F, a CD19/BCMA dual
CART-cell therapy, in adult subjects with relapsed/refractory Multiple Myeloma.
Age: 18 years - 66+
Gender: All
Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer
This phase II trial compares atezolizumab in combination with chemotherapy (docetaxel,
oxaliplatin, leucovorin calcium, fluorouracil, capecitabine) to atezolizumab alone for
controlling the growth and/or spreading of the disease in patients with gastric or
gastroesop...
Age: 18 years - 66+
Gender: All