A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) with and without renal involvement, idiopathic inflammatory myopathy (...
Age: 18 - 69 years
Gender: All
A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
The purpose of this study is to evaluate the efficacy, safety and drug levels of CC-97540
in participants with active systemic lupus erythematosus (SLE) including lupus nephritis
with inadequate response to glucocorticoids and at least 2 immunosuppressants.
Age: 16 years - 66+
Gender: All
An Open-Label, Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases
This is an open-label Phase 2 study evaluating the long term safety and tolerability of
GFB-887 in patients with focal segmental glomerulosclerosis (FSGS), and treatment-resistant
minimal change disease (TR-MCD)
Age: 18 - 75 years
Gender: All