A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
This is a first-in-human, single-arm, open-label study evaluating the safety,
tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases:
systemic lupus erythematosus (SLE) with and without renal involvement, idiopathic
inflammatory myopath...
Age: 18 - 74 years
Gender: All
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
The purpose of this trial is to evaluate the efficacy and safety of obecabtagene
autoleucel (obe-cel) administered once following lymphodepletion in participants with
severe, refractory systemic lupus erythematosus (SLE) and active lupus nephritis (LN).
Age: 12 - 65 years
Gender: All
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
This study will have two Phases: Phase 1a and Phase 1b. The goal of this clinical study
is to learn more about the study drug KITE-363, to establish dosing, tolerability,
safety, and preliminary efficacy of KITE-363 in participants with refractory autoimmune
diseases...
Age: 18 years - 66+
Gender: All
Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.
The purpose of this study is to determine if zigakibart is safe and effective for
long-term use in patients with immunoglobulin A nephropathy (IgAN). This is an extension
study for patients who have already completed an another zigakibart study.
Age: 18 - 100 years
Gender: All
An Open-Label, Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases
This is an open-label Phase 2 study evaluating the long term safety and tolerability of
GFB-887 in patients with focal segmental glomerulosclerosis (FSGS), and treatment-resistant
minimal change disease (TR-MCD)
Age: 18 - 75 years
Gender: All