Electrophysiological Read-Out of Interoceptive Processing
Interoception, or sensation from inside the body, is involved in a variety of clinical symptoms, such as tics, compulsions and negative mood. This study uses invasive recordings of brain activity and brain stimulation to better understand basic neural mechanisms of inte...
Human Epilepsy Project 3
Age: 18 years - 66+
By carrying a careful, large-scale and ambitious prospective study of a cohort of
participants with generalized epilepsy, the study team hopes to clarify the likelihood of
response and remission in this type of epilepsy, and try to explore the underlying biological
Invasive Decoding and Stimulation of Altered Reward Computations in Depression
Age: 13 years - 66+
Novel invasive neurostimulation stimulation strategies through neurosurgical interventions are emerging as a promising therapeutical strategy for major depressive disorder. These have been applied mostly to the anterior cingulate cortex, but other limbic brain regions h...
The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
Age: 18 - 80 years
Ketamine is a medication that came into clinical practice in the 1960's. Ketamine is used as an anesthetic and to provide pain relief. Recently, Ketamine was approved to treat drug resistant depression using subanesthetic doses. In the hospital setting, intravenous anes...
RNS System RESPONSE Study
Age: 18 years - 66+
To demonstrate that the RNS System is safe and effective as an adjunctive therapy in
individuals age 12 through 17 years with medically refractory partial onset epilepsy.
Biology of Juvenile Myoclonic Epilepsy
Age: 12 - 17 years
The investigators are collecting genetic information through blood samples as well as
clinical and EEG data from over 1000 people with Juvenile Myoclonic Epilepsy (JME) across the
UK, Europe and North America. This study will draw on both existing and new samples fr...
Age: 10 - 40 years