Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis
will be used to understand the natural history, underlying immunologic mechanisms, and
clinical implications of central nervous system (CNS) lesions, in particular lesions in
the ce...
Age: 18 years - 66+
Gender: All
A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases
The purpose of this study is to establish the tolerability, preliminary efficacy, and
pharmacokinetics of CC-97540 in participants with severe, refractory autoimmune diseases.
Age: 18 years - 66+
Gender: All
Biologics And Clinical Immunology Cohort at Sinai
The study team plans to establish a bioregistry of patients receiving biologic therapy as
part of their standard treatment at the Mount Sinai Therapeutic Infusion Center and
affiliated practices. The study team will to apply state-of-the-art approaches to assessing
...
Age: 12 years - 66+
Gender: All
The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
Determine the difference in the modified Rankin score at 16 weeks in participants with
anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis treated with "first-line"
immunomodulatory therapies provided as standard-of-care, and either inebilizumab
(investigational ...
Age: 12 years - 66+
Gender: All
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
This study is an access and distribution protocol for unlicensed cryopreserved cord blood
units (CBUs) in pediatric and adult patients with hematologic malignancies and other
indications.
Age: Birth - 66+
Gender: All