For Researchers: Advancing the Future of Healthspan
The average American celebrates just one healthy birthday after the age of 65; more than 90 percent of people head toward retirement with one or more chronic diseases. Mount Sinai scientists are redefining aging with rigorous research that aims to measure and modify biological signs of aging, such as inflammation and epigenetic changes. The goal is to slow aging at the source and prevent conditions like cancer, diabetes, heart disease, and Alzheimer’s that currently define many Americans’ later years.
Mount Sinai brings a nearly unmatched level of research expertise to the goal of extending healthspan. Ranked No. 11 nationwide in National Institutes of Health funding, the Icahn School of Medicine at Mount Sinai is in the 99th percentile in research dollars per investigator, according to the Association of American Medical Colleges. Mount Sinai scientists, educators, and clinicians are uniquely positioned to bring research from lab bench to clinical care settings and back again, bringing us closer to a future where aging doesn’t have to equal getting sick.
DigiTwin Project
The DigiTwin Project is a longitudinal precision health study at Mount Sinai that builds a comprehensive digital twin of each participant and uses AI foundation models to assess biological aging trajectories and identify emerging health risks before symptoms appear. The digital twins are built by integrating advanced multi-organ magnetic resonance imaging, continuous wearable sensing, digital biomarkers, retinal imaging, cognitive testing, physical fitness assessments, full clinical blood panels, multiomics profiling (proteomics, metabolomics, lipidomics, epigenetics, whole genome sequencing, gut microbiome), and environmental exposure monitoring.
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X Prize Healthspan
Mount Sinai’s team is a top-40 awardee and has been named semifinalists in this ongoing competition to revolutionize healthy aging by creating innovative therapies that restore muscle, cognitive, and immune function.
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Mount Sinai Million Health Discoveries Program
In what will be the largest genetic sequencing project of its kind, this program aims to enroll one million Mount Sinai patients to better understand how genes and the environment influence our health.
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