Adrenal Steroid Disorders Program
The Adrenal Steroid Disorders Program in the Department of Pediatrics at Icahn School of Medicine studies and treats a variety of disorders resulting from disruption of adrenal steroid metabolism including congenital adrenal hyperplasia, several types of low-renin hypertension, and intersex conditions. The Program Director is Maria I. New, MD, whose work in the area of steroid disorders spans 50 years. Dr. New and her team provide a very high standard of care in diagnosing and treating adrenal disorders, made possible by the knowledge and experience gained from years of clinical and laboratory research.
In addition to Dr. New, our team includes two physicians, a laboratory director, a psychoendocrinologist, and an endocrine fellow dedicated to providing comprehensive care. We operate an active endocrine clinic, enhanced by on-site DNA and hormone testing in labs supervised by Dr. New.
Our team also provides comprehensive prenatal diagnosis and treatment including genetic counseling. Dr. New and her colleagues run a weekly endocrine clinic, providing a high standard of care for infants, children and young adults presenting with symptoms of endocrinopathies such as:
- Congenital Adrenal Hyperplasia owing to 21-hydroxylase deficiency, 11ß-hydoxylase deficiency, 3ß-hydroxysteroid deficiency and 17a-hydroxylase deficiency
- Prenatal Diagnosis and Treatment for 21-hydroxylase deficiency and 11ß-hydoxylase deficiency congenital adrenal hyperplasia
- Apparent Mineralocorticoid Excess (11ß-hydoxysteroid deficiency type 2) and other forms of monogenic low renin hypertension
- Androgen Insensitivity and other disorders of steroid resistance
- Steroid 5a-reductase 2 deficiency
- 17ß-hydroxysteroid Dehydrogenase Deficiency
- Cushing's Disease
- Addison's Disease
- Polycystic ovary syndrome
- Disorders of sexual differentiation
- Diagnosis and treatment of gender disorders
- Hyperandrogenemic symptoms including: in children, early pubic hair, precocious puberty, crossing two upward centiles of growth, tall stature, and early arrest of growth; in adolescents, acne, early arrest of growth, and short stature; in adults, reduced fertility; in females only, hirsutism, irregular menstrual periods and polycystic ovaries; and in males only, adrenal rest tumors in testes
- Short stature
- Pituitary disease
- Russell Silver Syndrome
- Failure to thrive
- Growth failure related to gestational growth restriction
- Early exposure to sex steroids
- Growth hormone/IGF-1 deficiency and resistance
- Growth hormone therapy in both children and adults
- Sex chromosome disorders
- Thyroid disorders including neonatal hypo- and hyperthyroidism
A psychoendocrinologist is available to counsel patients and parents of patients who are struggling with the psychological ramifications of living with an adrenal disorder.
Dr. New has been honored for her work by election to the National Academy of Sciences and National Institute of Child Health and Human Development Hall of Honor. She is the recent recipient of the prestigious IPSEN Award. She has published more than 640 academic articles in a wide range of prestigious journals and a genetics book entitled Genetic Steroid Disorders published by Elsevier in October 2013.
For appointments or more information:
Research and Academic