Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and
bleeding from the lining of the rectum and colon (large intestine). This study will assess
how safe and effective Upadacitinib is in treating pediatric participants with UC....
Age: 2 - 17 years
Gender: All
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis
The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the
drug in pediatric participants with moderately to severely active ulcerative colitis (UC).
Age: 2 - 17 years
Gender: All
ABTECT - Maintenance
This is a multicenter, randomized study to evaluate the long-term efficacy and safety of
ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with
moderately to severely active ulcerative colitis who have inadequate response, no respo...
Age: 16 years - 66+
Gender: All
ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and
safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with
moderately to severely active ulcerative colitis who have inadequate response, no respon...
Age: 16 years - 66+
Gender: All
The GORE® VIAFORT Vascular Stent Iliofemoral Study
This study is a prospective, non-randomized, multicenter, single-arm, clinical study to
evaluate the performance, safety and efficacy of the GORE® VIAFORT Vascular Stent for
treatment of symptomatic iliofemoral venous obstruction.
Age: 18 years - 66+
Gender: All
The GORE® VIAFORT Vascular Stent IVC Study
This study is a prospective, multicenter, non-randomized, single-arm study to evaluate the
performance, safety, and efficacy of the GORE® VIAFORT Vascular Stent for treatment of
symptomatic inferior vena cava obstruction with or without combined iliofemoral obstruct...
Age: 18 years - 66+
Gender: All
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in
pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will
last about 172 weeks and may include up to 44 visits.
Age: 2 - 19 years
Gender: All
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK)
of tofacitinib in pediatric participants with moderately to severely active UC. In the US and
EU, patients with prior TNFi failure or intolerance will be enrolled. Outside of...
Age: 2 - 17 years
Gender: All
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical gra...
Age: 18 years - 66+
Gender: All
Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)
A Randomized Controlled Multicenter Clinical Trial, Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®) and Standard of Care versus Standard of Care alone in the healing Chronic Diabetic Foot Ulcers. Multi-center, open label, randomized controlled tr...
Age: 18 years - 66+
Gender: All
Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)
A Randomized Controlled Multicenter Clinical Trial, Evaluating the Efficacy of Dual Layer
Amniotic Membrane (Artacent®) and Standard of Care versus Standard of Care alone in the
healing Chronic Diabetic Foot Ulcers. Multi-center, open label, randomized controlled tr...
Age: 18 years - 66+
Gender: All
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis
The purpose of this study is to evaluate the efficacy and safety of mirikizumab as
maintenance therapy in participants who completed prior 12-week induction study AMAN
(NCT03518086).
Age: 18 - 80 years
Gender: All
The Mount Sinai Diabetic Foot Ulcer Prospective Trial
The purpose of this study is to evaluate whether placing stent(s) for a blockage in a leg
vein will help improve the healing of diabetic foot ulcers (DFU). The investigators know from
having taken care of many patients with diabetic foot ulcers that it is a major ca...
Age: 30 - 64 years
Gender: All
PriMatrix for the Management of Diabetic Foot Ulcers
The study will evaluate the efficacy of PriMatrix Dermal Repair Scaffold in the management of diabetic foot ulcers in subjects with diabetes mellitus versus the Standard of Care treatment. Half of patients will be treated using PriMatrix while the other half will receiv...
Age: 18 years - 66+
Gender: All
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in
patients with moderately to severely active UC who are treated as recommended in the product
label.
Age: 18 - 99 years
Gender: All