Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors
This is a first-in-human, open-label, multicenter, Phase 1 study to evaluate the safety,
tolerability and preliminary efficacy of IPH4502 and to determine the recommended Phase 2
dose (RP2D) in advanced solid tumors that are known to express Nectin-4
Age: 18 years - 66+
Gender: All
Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer
This phase II trial compares atezolizumab in combination with chemotherapy (docetaxel,
oxaliplatin, leucovorin calcium, fluorouracil, capecitabine) to atezolizumab alone for
controlling the growth and/or spreading of the disease in patients with gastric or
gastroesop...
Age: 18 years - 66+
Gender: All
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study
to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080
monotherapy (HLA-G inhibitor) and in combination with either pembrolizumab (PD-1
inhibitor), cetuxim...
Age: 18 years - 66+
Gender: All
A Phase II Trial of Neoadjuvant Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) With Chemoradiation
Stomach cancer is the fifth most common digestive cancer and third main cause of death
from cancer in the world. Modern management of Gastric cancer involves a
multi-disciplinary approach involving surgical oncologists, medical oncologists,
gastroenterologists and on...
Age: 18 years - 66+
Gender: All
A Phase II Trial of Neoadjuvant Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) With Chemoradiation
Stomach cancer is the fifth most common digestive cancer and third main cause of death from
cancer in the world. Modern management of Gastric cancer involves a multi-disciplinary
approach involving surgical oncologists, medical oncologists, gastroenterologists and
...
Age: 18 years - 66+
Gender: All