A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation
This is a multi-center, non-randomized, concurrent controlled, multi-arm, Phase 1
interventional, open-label, biologic assignment-based umbrella study evaluating the
feasibility, safety and preliminary efficacy of an escalating dose regimen of up to 2
doses of TSC-10...
Age: 18 years - 66+
Gender: All
A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation
A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in adult
patients with acute leukemia.
Age: 18 years - 66+
Gender: All
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia
In this trial, ziftomenib, a menin-MLL(KMT2A) inhibitor, will be tested in patients for
the first time. The trial includes a Main Study and four sub-studies. In the Main Study
(including Phase 1a, Phase 1b, and Phase 2 portions), ziftomenib will be evaluated in
patie...
Age: 18 years - 66+
Gender: All
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
This study is an access and distribution protocol for unlicensed cryopreserved cord blood
units (CBUs) in pediatric and adult patients with hematologic malignancies and other
indications.
Age: Birth - 66+
Gender: All