Virtual Reality for Pain Control in US-Guided Obstetric Needle Procedures
This is a single-site randomized controlled pilot study at Mount Sinai Hospital
evaluating the effect of virtual reality on procedural pain and anxiety in obstetric
patients undergoing ultrasound-guided needle procedures. Patients will be randomized to
receive either...
Age: 18 years - 66+
Gender: Female
Acute Migraine Treatment in the ED With Gepants
This study evaluates the effectiveness of rimegepant 75 mg orally disintegrating tablet
(ODT) single-dose or zavegepant 10 mg nasal spray single-dose as acute migraine
treatments during Emergency Department (ED) encounters. Although these two calcitonin
gene-related ...
Age: 18 years - 66+
Gender: All
Acute Migraine Treatment in the ED With Gepants
This study evaluates the effectiveness of rimegepant 75 mg orally disintegrating tablet (ODT) single-dose or zavegepant 10 mg nasal spray single-dose as acute migraine treatments during Emergency Department (ED) encounters. Although these two calcitonin gene-related pep...
Age: 18 years - 66+
Gender: All
Treatment of Moderate to Severe Refractory Crohn's Disease
This research study is testing an investigational research product called TRX103 as a
possible treatment for individuals suffering from Crohn's Disease (CD). The primary
purpose of this study is to learn how safe and effective different doses of TRX103 are
when admin...
Age: 18 - 65 years
Gender: All
Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy
A randomized double-blind placebo controlled trial comparing the effect of a combined
ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block
on procedure related pain with office hysteroscopies.
Age: 18 years - 66+
Gender: Female
Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy
A randomized double-blind placebo controlled trial comparing the effect of a combined
ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block
on procedure related pain with office hysteroscopies.
Age: 18 years - 66+
Gender: Female
Healing Track Clinical Trial
This is a randomized clinical trial to evaluate a digital pain reprocessing therapy (PRT)
intervention for chronic back pain (CBP).
The purpose of this research is to test whether a new digital treatment for chronic pain
works as well as traditional treatments for ...
Age: 21 - 70 years
Gender: All
Healing Track Clinical Trial
This is a randomized clinical trial to evaluate a digital pain reprocessing therapy (PRT)
intervention for chronic back pain (CBP).
The purpose of this research is to test whether a new digital treatment for chronic pain
works as well as traditional treatments for ...
Age: 21 - 70 years
Gender: All
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most frequently affecting the bowels. It can cause
many different symptoms including belly pain, diarrhea, tiredness, and weight loss.
Treatmen...
Age: 18 - 75 years
Gender: All
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most frequently affecting the bowels. It can cause
many different symptoms including belly pain, diarrhea, tiredness, and weight loss.
Treatmen...
Age: 18 - 75 years
Gender: All
Behavioral Therapy for Crohn's Disease
People living with Crohn's disease (CD) experience psychological and emotional symptoms,
in addition to known chronic and disabling physical symptoms, which prevent them from
living their life to the fullest (flourishing). Depression and anxiety are experienced by
30...
Age: 18 - 65 years
Gender: All
Behavioral Therapy for Crohn's Disease
People living with Crohn's disease (CD) experience psychological and emotional symptoms,
in addition to known chronic and disabling physical symptoms, which prevent them from
living their life to the fullest (flourishing). Depression and anxiety are experienced by
30...
Age: 18 - 65 years
Gender: All
Intrathecal Dexmedetomidine Vs Epinephrine
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose
spinal analgesia preparations improves the length and/or speed of onset of the sensory
block and post-operative pain management without increased negative side effects. To
date, howe...
Age: 18 - 55 years
Gender: Female
Intrathecal Dexmedetomidine vs Epinephrine
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose
spinal analgesia preparations improves the length and/or speed of onset of the sensory
block and post-operative pain management without increased negative side effects. To
date, howe...
Age: 18 - 55 years
Gender: Female
Virtual Reality (VR) Self-Hypnosis Software
This single-site study of self-hypnosis software using an off-the-shelf virtual reality
(VR) device (OculusGo™) to determine the software's safety, usability, and preliminary
efficacy in pain relief for HIV-associated chronic pain patients. This is funded under
the i...
Age: 18 years - 66+
Gender: All
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most often affecting the bowels. It can cause many
different symptoms including abdominal pain, diarrhea, tiredness, and weight loss. This
stud...
Age: 2 - 17 years
Gender: All
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness,
swelling), in the digestive tract, most often affecting the bowels. It can cause many
different symptoms including abdominal pain, diarrhea, tiredness, and weight loss. This
stud...
Age: 2 - 17 years
Gender: All
Behavioral and Cognitive Predictors of Persistent Pain and Opioid Misuse in Chronic Pain
Chronic lower back pain (CLBP) affects approximately 20% of the global population. The study objective is to determine if impulsivity, inhibitory control, drug choice, and/or cognitive distortions predict opioid misuse and disability in patients with chronic pain. This ...
Age: 18 years - 66+
Gender: All
Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery
Having spine surgery and recovery is a vulnerable period when opioid naive patients may
transition into long-term use of opioids, and when previously opioid tolerant patients
may be at risk to continue towards long-term opioid use and dependence. However, little
is k...
Age: 18 years - 66+
Gender: All
Behavioral and Cognitive Predictors of Persistent Pain and Opioid Misuse in Chronic Pain
Chronic lower back pain (CLBP) affects approximately 20% of the global population. The
study objective is to determine if impulsivity, inhibitory control, drug choice, and/or
cognitive distortions predict opioid misuse and disability in patients with chronic pain.
Th...
Age: 18 years - 66+
Gender: All