The study is a prospective, longitudinal, non-interventional, multicenter study of participants with HNSCC who will have tissue and blood based molecular biomarker profiling during their standard of care treatment.
Age: 18 years - 66+
Gender: All
We've found 8 total result s for "Head and Neck Neoplasms".
This is a Phase 1/2, open-label, multi-center, single arm basket study evaluating the administration of PVSRIPO ± anti programmed cell death protein 1 (PD 1)/programmed death-ligand 1 (PD L1) monoclonal antibody (mAb) (which will be referred to throughout this pro...
Age: 18 years - 66+
Gender: All
An open-label, controlled, multi-site, interventional, 2-arm, Phase II/III trial of BNT113 in combination with pembrolizumab vs pembrolizumab monotherapy as first line treatment in patients with unresectable recurrent or metastatic HPV16+ HNSCC expressing programmed ...
Age: 18 years - 66+
Gender: All
An open-label, controlled, multi-site, interventional, 2-arm, Phase II trial of BNT113 in combination with pembrolizumab vs pembrolizumab monotherapy as first line treatment in patients with unresectable recurrent or metastatic HPV16+ HNSCC expressing programmed cell...
- Carcinoma
- Carcinoma, Squamous Cell
- Head and Neck Neoplasms
- Squamous Cell Carcinoma of Head and Neck
- Papilloma
- Recurrence
Age: 18 years - 66+
Gender: All
TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy (HLA-G inhibitor) and in combination with either pembrolizumab (PD-1 inhibitor), cetuxim...
- Neoplasms
- Ovarian Neoplasms
- Endometrial Neoplasms
- Uterine Cervical Neoplasms
- Kidney Neoplasms
- Squamous Cell Carcinoma of Head and Neck
- Prostatic Neoplasms
- Colorectal Neoplasms
- Stomach Neoplasms
- Breast Neoplasms
- Urinary Bladder Neoplasms
- Adenocarcinoma of Lung
- Melanoma
- Neoplasm Metastasis
- Carcinoma, Renal Cell
- Triple Negative Breast Neoplasms
- Head and Neck Neoplasms
- Lung Neoplasms
Age: 18 years - 66+
Gender: All
Head and neck oncologic surgery often requires the use of free tissue transfer, or microvascular reconstruction, to reconstruct defects created by tumor resections. Although there are several techniques for the reconstruction of defects, resection of large tumors lea...
Age: 18 years - 66+
Gender: All
This is a phase 3 randomized, placebo controlled study to evaluate the safety and anti-tumor activity of Avelumab in combination with standard of care chemoradiation (SoC CRT) versus SoC CRT alone in front-line treatment of patients with locally advanced head and neck...
Age: 18 years - 66+
Gender: All
This research study is a Phase I clinical trial. Phase I clinical trials test the safety of an investigational drug. Phase I studies also try to define the appropriate dose of the investigational drug to use for further studies. "Investigational" means that the drug i...
Age: 18 years - 66+
Gender: All