Infectious Diseases

Mpox Vaccine Information

Vaccination against mpox (formerly known as monkeypox) is available to eligible people.

Mpox is an infectious disease that's currently spreading in the United States. It's transmitted through close contact and causes a rash on various parts of the body. You can learn more about mpox and what to do if you may have been exposed from New York City and the Centers for Disease Control and Prevention.

Vaccination Eligibility

If you have been exposed to mpox, getting vaccinated may keep you from getting sick. Vaccination is most effective within four days of exposure but can help up to 14 days later.

Vaccine is currently available for at-risk populations, defined by the New York City Department of Health and Mental Hygiene (DOHMH). To be eligible to receive the vaccine, you must meet any of the following criteria:

  • People of any sexual orientation or gender identity who have or may have multiple or anonymous sex partners, or participate or may participate in group sex
  • People of any sexual orientation or gender identity whose sex partners are eligible per the criteria above
  • People who know or suspect they have been exposed to mpox in the last 14 days
  • Anyone else who considers themselves to be at risk for mpox through sex or other intimate contact.

How to Get Vaccinated Against Mpox

Appointments for the JYNNEOS™ vaccine are available through the New York City vaccine site. We are also offering mpox vaccination on a walk-in basis at the Mount Sinai-Union Square Urgent Care location, Monday-Friday from 8 am to 7 pm.

In accordance with DOHMH guidance, most patients will receive an injection just below the skin in your forearm, similar to a tuberculosis test. This is known as an “intradermal” injection. If there is a reason why you should not receive an intradermal injection, you will be asked about it before you receive the vaccine. Learn more about intradermal vaccination here.

Please note that patients under 18 will need consent from a parent or legal guardian, and patients 15 and under must be accompanied by a parent or legal guardian.

Further Information About Mpox Vaccines