The Tether™ - Vertebral Body Tethering System Post Approval Study

ID#: NCT04505579

Age: Birth - 66+

Gender: All

Healthy Subjects: No

Recruitment Status: Recruiting

Start Date: October 29, 2020

End Date: December 31, 2027

Contact Information:
Monica Barascout, BS
1-303-465-8960
Kim Martinez
1-303-465-8960
Summary: This study is an opportunity to provide continued reasonable assurance of the safety and probable benefit of The Tether HUD. The study will collect long term safety and efficacy information from patients who have had their idiopathic scoliosis treated via anterior vertebral body tethering (AVBT) with The Tether.
Eligibility:

Inclusion Criteria:

- Diagnosis of progressive idiopathic scoliosis

- Skeletally immature, based on both Risser (<5) and Sanders (<8) assessments

- Major Cobb angle ≥30° and ≤65°

- Osseous structure dimensionally adequate to accommodate screw fixation, as determined by radiographic imaging

- Failed or intolerant to bracing

Exclusion Criteria:

- Presence of any systemic infection, local infection, or skin compromise at the surgical site

- Prior spinal surgery at the level(s) to be treated

- Documented poor bone quality, defined as a T-score -1.5 or less

- Any other medical or surgical condition which would preclude the potential benefit of spinal surgery, such as coagulation disorders, allergies to the implant materials, and patient's unwillingness or inability to cooperate with post-operative care instructions

- Unwillingness, inability, or living situation (e.g. custody arrangements, homelessness, detention) that would preclude ability to return to the study site for follow-up visits as described in protocol and Informed Consent

- Unwillingness to sign Informed Consent Form and participate in study procedures