Alnuctamab for Refractory SLE (LATTE Study)
This study will assess the safety and preliminary efficacy of the bi-specific TCE,
alnuctamab (known as BMS-986349, CC-93269, EM901), targeting BCMA in patients with
moderate to severe SLE, refractory to standard-of-care treatments.
Age: 18 - 60 years
Gender: All
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) with and without renal involvement, idiopathic inflammatory myopathy (...
Age: 18 - 69 years
Gender: All
A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
The purpose of this study is to evaluate the efficacy, safety and drug levels of CC-97540
in participants with active systemic lupus erythematosus (SLE) including lupus nephritis
with inadequate response to glucocorticoids and at least 2 immunosuppressants.
Age: 16 years - 66+
Gender: All
A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)
The purpose of this study is to establish the tolerability, preliminary efficacy, and
pharmacokinetics of CC-97540 in participants with severe, refractory autoimmune diseases
(Breakfree-1).
Age: 18 years - 66+
Gender: All