Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
Sphere-9 VT EFS is a prospective, multi-center, non-randomized, unblinded feasibility
study. Adult subjects with recurrent, sustained, scar-related monomorphic ventricular
tachycardia will be enrolled and treated with the Sphere-9 Catheter and Affera Ablation
System.
Age: 18 - 85 years
Gender: All
Abbott Structural Heart Device Registry
The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting. The Registry primarily involves gathering data from routine hospital practices and standard-of-care (SOC) proc...
Age: Birth - 66+
Gender: All
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin
(TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that
accumulates in different organs in the body and can cause damage to the organ. There are
two way...
Age: 18 - 75 years
Gender: All
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/m^2 or higher and Atherosclero...
Age: 45 years - 66+
Gender: All
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
This is a prospective, multi-center, open label, randomized control clinical trial
evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in
NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial).
The study contains of 5 arms:
...
Age: 18 years - 66+
Gender: All
Rectus Sheath Block in Cardiac Surgery
This is a prospective, randomized study. The purpose of this study is to evaluate the
effect of post-surgical pain control of a type of peripheral nerve block, Rectus Sheath
Block.
1. Does the rectus sheath block decrease opioid consumption postoperatively after
...
Age: 18 - 85 years
Gender: All
MINDS Imaging Ancillary Study
This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN)
"Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart
Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30
years...
Age: 18 - 30 years
Gender: All
Assessment of Patterns of Patient Reported Outcomes in Adults With Congenital Heart Disease - International Study II
This is an international, cross-sectional and descriptive study that aims to investigate differences in patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) and that aims to explore the profile and healthcare needs of adults with co...
Age: 18 years - 66+
Gender: All