Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
The purpose of this study is to comprehensively characterize PMS using standardized medical,
cognitive, and behavioral measures and to track the natural history of the syndrome using
repeated longitudinal assessments. In addition, this study will be aiming to identi...
Age: 18 months - 66+
Gender: All
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
Social cognition impairment is critical to the pathology and morbidity of a number of
psychiatric disorders, including the schizophrenia spectrum, the autism spectrum and the
personality disorders, thus representing a dimension consistent with RDoC. As such, this
stu...
Age: 18 - 65 years
Gender: All
A Pilot Treatment Study of Insulin-Like Growth Factor-1 (IGF-1) in Autism Spectrum Disorder
The proposed project will pilot the use of IGF-1 as a novel treatment for core symptoms of
autism. We will use a double-blind, placebo-controlled crossover trial design in five
children with autism to evaluate the impact of IGF-1 treatment on autism-specific impairm...
Age: 5 - 12 years
Gender: All