Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
This is a phase 2, randomized, multiple-dose, placebo-controlled study designed to
evaluate the safety, efficacy, and pharmacokinetics (PK) of CSL889 (human hemopexin) when
given intravenously (IV) to adults and adolescents with sickle cell disease (SCD)
experiencing...
Age: 12 years - 66+
Gender: All
Nafamostat Efficacy in Phase 3 Registrational CRRT Study
A prospective, randomized, placebo-controlled clinical study to investigate the safety
and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood
circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate
hepari...
Age: 18 - 80 years
Gender: All
A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease
This parallel-group, randomized, placebo-controlled study will examine the incidence and
severity of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) stage
III/IV following an i.v. injection of iso-osmolar iodinated contrast material iodixanol
...
Age: 18 years - 66+
Gender: All