Conditions We Treat

Mount Sinai's Division of Rheumatology provides advanced treatments for rheumatic diseases and related disorders such as the following.

  • Amyloidosis: A rare condition, amyloidosis occurs when proteins called amyloids build up in tissues or organs, most often the kidneys, heart, spleen, liver, gastrointestinal tract, and nervous system. Symptoms vary depending on the organ affected, but can include leg swelling, weakness or fatigue, weight loss, shortness of breath, and tingling or numbness in the hands or feet.
  • Ankylosing spondylitis: A chronic inflammatory disease, ankylosing spondylitis causes arthritis of the joints, mainly in the hips and spine. This condition can also cause inflammation of the heart valves, lungs, or eyes.
  • Behcet's disease: A rare, chronic condition, Behcet's disease involves the inflammation of blood vessels throughout the body. It is marked by recurring eye inflammation and oral and genital ulcers.
  • Gout: This condition results from the build-up of uric acid crystals in the joints, which causes the joints to become inflamed. Pseudogout is a type of arthritis that occurs when calcium crystals, called calcium pyrophosphates, build up in the fluid surrounding joints.
  • Inflammatory muscle disease: Two forms of inflammatory muscle disease include polymyositis (an uncommon inflammatory disease of the skeletal muscles causing weakness, swelling, and damage) and dermatomyositis (a muscle disease marked by inflammation and skin rash). Symptoms of these conditions include difficulty swallowing and muscle pain and weakness.
  • Lupus: Systemic lupus erythematosus (SLE) is a chronic, complex disease involving inflammation that can affect the joints, skin, organs (such as kidneys and lungs), and nervous system. Most commonly occurring in women, symptoms can range from mild to severe and include rashes, fatigue, arthritis, and fever. Most patients experience periods of active disease followed by remission.
  • Osteoarthritis: A joint disease typically affecting people who are middle-aged or elderly, ostearthritis (OA), is characterized by deterioration of the cartilage, ligaments, and bone. This form of arthritis most commonly occurs in the hand joints, hips, spine, knees, and large toes. Symptoms vary between patients but can include pain, stiffness, and swelling of the affected joint.
  • Polymyalgia rheumatica: An inflammatory disorder, polymyalgia rheumatica (PMR) causes muscle pain and stiffness in the body, most commonly affecting the shoulders, hips, arms, and thighs.
  • Rheumatoid arthritis: The most common type of autoimmune arthritis, rheumatoid arthritis (RA) is a chronic condition that involves joint pain, stiffness, and swelling, most often in the hands and feet. Symptoms include stiffness that is worse in mornings, loss of energy, loss of appetite, and low fevers.
  • Scleroderma: A rare disease of the connective tissue, scleroderma can cause the tissue in joints, internal organs, and skin to thicken and soften.
  • Sjogren's syndrome: An inflammatory disease that can involve many parts of the body, Sjogren's syndrome most commonly affects the saliva and tear glands, causing symptoms that include eye irritation, dry mouth, swelling of the glands around the neck and face, and difficulty swallowing. This condition can sometimes develop as a complication of another rheumatologic disease, such as RA or lupus.
  • Wegener's Granulomatosis: A rare condition, Wegener's granulomatosis (WG) causes the walls of blood vessels to become inflamed (called vasculitis), limiting blood flow to tissues. This disease can affect any organ in the body.