Reifenstein syndrome

PAIS; Androgen insensitivity syndrome - partial; Incomplete testicular feminization; Type I familial incomplete male pseudohermaphroditism; Lubs syndrome; Reifenstein syndrome; Rosewater syndrome; Partial androgen insensitivity syndrome - Intersex; Differences of sex development

Partial androgen insensitivity syndrome (PAIS) is when a person who has one X and one Y chromosome (typically seen in males) but is resistant to hormones that produce a male appearance (called androgens). As a result, the person has some of the physical traits of a female, but the genetic makeup of a male.

PAIS is a type of androgen insensitivity syndrome (AIS). AIS is one of the conditions that are described as differences of sex development (DSD).

Male reproductive system

The male reproductive system, viewed from a sagittal section.



Exams and Tests


Support Groups

Outlook (Prognosis)

Possible Complications

When to Contact a Medical Professional