Androgen insensitivity syndrome

Testicular feminization; AIS - complete; AIS - partial; AIS - mild; Androgen insensitivity syndrome - differences of sex development; Androgen insensitivity syndrome - Intersex

Androgen insensitivity syndrome (AIS) is when a person who has one X and one Y chromosome (typically seen in males) is resistant to hormones that produce a male appearance (called androgens). As a result, the person has some of the physical traits of a female, but the genetic makeup of a male.

Androgen insensitivity syndrome is one of the conditions that are described as differences of sex development (DSD).

Male reproductive anatomy

The male reproductive structures include the penis, the scrotum, the testes, the epididymis, the seminal vesicles, and the prostate.

Female reproductive anatomy

Internal structures of the female reproductive anatomy include the uterus, ovaries, and cervix. External structures include the labium minora and majora, the vagina and the clitoris.

Female reproductive anatomy

The female reproductive organs are located in the lower abdomen.


Karyotyping is a test used to identify chromosome abnormalities as the cause of malformation or disease. The test can be performed on a sample of blood, bone marrow, amniotic fluid, or placental tissue.



Exams and Tests


Support Groups

Outlook (Prognosis)

Possible Complications

When to Contact a Medical Professional