Cognitive Reappraisal Training

ID#: NCT04967222

Age: 18 - 55 years

Gender: All

Healthy Subjects: No

Study Phase: N/A

Recruitment Status: Recruiting

Start Date: July 01, 2021

End Date: June 01, 2022

Contact Information:
Harold W Koenigsberg, MD
Cameryn A Cooley, BA
Summary: Previous work by the study group convinced the study team to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based treatments of BPD. The present proposal aims to refine and test a proposed clinical intervention for BPD patients, training in reappraisal-by-distancing, in terms of its ability to influence hypothesized neural and behavioral targets and, once that is established, to demonstrate its ability improve clinically relevant outcome measures.

Inclusion Criteria:

- Medically healthy men and women with Borderline Personality Disorder who are mentally competent and give informed voluntary written consent.

Exclusion Criteria:

- Age > 55

- Criteria for Schizotypal Personality Disorder or Avoidant Personality Disorder. SPD is excluded to avoid possible confound from the restricted affect that characterizes SPD and co-morbid AvPD subjects will be excluded because the researchers have shown that their patterns of neural activity in emotion processing are distinct from BPD subjects.